Xian-Jin Xie, PhD

Associate Professor
Department of Clinical Sciences, Simmons Comprehensive Cancer Center

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

xian-jin.xie@utsouthwestern.edu

Biography

Dr. Xie joined the Department of Clinical Sciences (then Center for Biostatistics and Clinical Science) and Simmons Comprehensive Cancer Center in June, 2005. He previously was an associate research scientist at the University of Iowa.

Dr. Xie’s research focuses on biostatistical methodologies and the application of those methodologies to collaborative research between biomedical and clinical disciplines. He earned a Doctorate and Master’s degree in biostatistics, as well as a Master’s degree in neurobiology, from the University of Iowa. Dr. Xie received his bachelor’s degree from Beijing University in China.

Education

Graduate SchoolUniversity of Iowa (2005)

Research Interests

Clinical trials methodologies
Collaborative cancer research and bioinformatics
Statistical methods on correlated data
Statistical model diagnosis and goodness-of-fit tests
Survival analysis and categorical data analysis

Publications

Increasing the power: Goodness-of-fit tests for ordinal logistic regression models with continuous covariates

Xie XJ and Bian A , JP Journal of Biostatistics , October 2009; (3(3)):225-246

Increasing the power: A practical approach to Goodness-of-Fit test for logistic regression models with continuous predictors

Xie XJ, Pendergast J and Clarke WR , Computational Statistics & Data Analysis , January 2008; (52(5)):2703-2713

Synthetic lethal screen identification of chemosensitizer loci in cancer cells

Whitehurst AW, Bodemann BO, Cardenas J, Ferguson D, Girard L, Payton M, Minna JD, Michnoff C, Hao W, Roth MG, Xie X-J, White MA , Nature , April 2007; (446 (7137)):815-819

Bayesian optimal discovery procedure for simultaneous significance testing

Cao J, Xie XJ, Zhang S, Whitehurst A, White M , BMC Bioinformatics , 2009; (doi: 10.1186/1471-2105-10)

Accounting for intraclass correlations and controlling for baseline differences in a cluster-randomized evidence based practice intervention study

Xie XJ, Titler M, and Clarke WR , Worldviews on Evidence-Based Nursing , 2008; (5(2)):95-101

Professional Associations/Affiliations

American Statistical Association

International Biometric Society (ENAR)

Society for Clinical Trials

The Society for Neuroscience (former member)