Sandeep Burma, PhD

Assistant Professor
Radiation Oncology
Graduate Program: Cancer Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-7600

sandeep.burma@utsouthwestern.edu

Education

Graduate SchoolNational Institute of Immunology, New Delhi, India (1995)

Research Interests

Genetic basis of radioresistance of glioblastomas
Particle radiation and carcinogenesis (NASA)
Sensing, signaling, and repair of DNA double-strand breaks

Publications

Targeting Non-Homologous End-Joining Through Epidermal Growth Factor Receptor Inhibition: Rationale and Strategies for Radiosensitization

B. Mukherjee, H. Choy, C. Nirodi, and S. Burma , Seminars in Radiation Oncology , October 2010; (20):250-257

Modulation of the DNA-damage response to HZE particles by shielding

B. Mukherjee, C.V. Camcho, N. Tomimatsu, J. Miller, and S. Burma , DNA Repair , October 2008; (7):1717-1730

EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma

B. Mukherjee, B. McEllin, C.V. Camacho, N. Tomimatsu, S. Sirasanagandala, S. Nannepaga, K.J. Hatanpaa, B. Mickey, C. Madden, E. Maher, D.A. Boothman, F. Furnari, W.K. Cavenee, R.M. Bachoo, and S. Burma , Cancer Research , May 2009; (69):4252-4259

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells

N. Tomimatsu, B. Mukherjee, and S Burma , EMBO Reports , June 2009; (10):629-635

Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks

C. V. Camacho, B. Mukherjee, B. McEllin, L-H. Ding, B. Hu, A. Habib, X-J. Xie, C. Nirodi, D. Saha, M. Story, A. Balajee, R. M. Bachoo, D. A. Boothman, and S. Burma , Carcinogenesis , July 2010; (31):1889-1896

PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or PARP Inhibitors

B. McElliin, C.V. Camacho, B. Mukherjee, B. Hahm, N. Tomimatsu, R.M. Bachoo, and S. Burma , Cancer Research , July 2010; (70):5457-5464

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells.

Mukherjee B, Kessinger C, Kobayashi J, Chen BP, Chen DJ, Chatterjee A, Burma S, DNA repair, 2006 May; 5 (5):575-90

Honors/Awards

Cancer Prevention and Research Institute of Texas (CPRIT)

Individual Investigator Award (2010)

Japan Society for Promotion of Science (JSPS)

Financial support for lecture-tour of Japan (2009)

Department of Defense Breast Cancer Research Program (DOD BCRP)

Concept Award (2003)

Eighth International Workshop for Ataxia Telangiectasia (ATW)

Best Abstract Award (1999)

Council for Scientific and Industrial Research of India (CSIR)

Research Fellowship (1990)

Professional Associations/Affiliations

American Association for the Advancement of Science (AAAS)

American Association of Cancer Research (AACR)

Environmental Mutagen Society (EMS)

Radiation Research Society (RRS)