Autophosphorylation of DNA-PKcs regulates its dynamics at DNA double-strand breaks

Naoya Uematsu, Eric Weterings, Ken-ichi Yano, Keiko Morotomi-Yano, Burkhard Jakob, Gisela Taucher-Scholz, Pierre-Olivier Mari, Dik C. van Gent, Benjamin P. C. Chen, and David J. Chen , J. Cell Biol. , 2007; (177):219-29

ATM is essential for phosphorylation of DNA-PKcs at T2609 cluster upon DNA double strand break

Benjamin P.C. Chen, Naoya Uematsu, Junya Kobayashi, Yaniv Lerenthal, Hirohiko Yajima, Andrea Krempler, Markus Lobrich, Yossi Shiloh, David J. Chen , J. Biol. Chem. , 2007; (282):6582-6587

ATR-dependent DNA-PKcs phosphorylation in response to UV-induced replication stress

Yijima, Kyung-Jong Lee, and Benjamin P.C. Chen , Molecular & Cellular Biology , 2006; (26):7520-8

Cell Cycle Dependence of DNA-PK phosphorylation in Response to DNA Double Strand Breaks

Benjamin P.C. Chen, Doug W. Chan, Junya Kobayashi, Sandeep Burma, Aroumougame Asaithamby, Keiko Yano, Elliot Botvinick, Jun Qin, and David J. Chen , J. Biol. Chem , 2005; (280):14709-15

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

Doug W. Chan, Benjamin P.C. Chen, Sheela Prithivirajsingh, Akihiro Kurimasa, Michael D. Story, Jun Qin, and David J. Chen. , Gene & Development , 2002; (16):2333-2338

Involvement of DNA dependent protein kinase in normal cell cycle progression through mitosis

Kyung-Jong Lee, Yu-Fen Lin, Han-Yi Chou, Hirohiko Yajima, Kazi R. Fattah, Sheng-Chung Lee, and Benjamin P.C. Chen , J. Biol. Chem. , 2011; (286):12796-12802

Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and spontaneous chromosomal numerical instability

Hatsumi Nagasawa, John B. Little, Yu-Fen Lin, Sairei So, Akihiro Kurimasa, Yuanlin Peng, John R. Brogan, David J. Chen, Joel S. Bedford, and Benjamin P. C. Chen , Radiation Research , 2011; (175):83-89

Severe anemia and stem cell failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

Shichuan Zhang, Hirohiko Yajima, HoangDinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, Andre Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen , J. Cell Biol. , 2011; (193):295-305

An Orthotopic Lung Tumor Model for Image-Guided Stereotactic Irradiation in Rats

Debabrata Saha, Linda Watkins, Yi Yin, Philip Thorpe, Michael D. Story, Kwang Song, Pavithra Raghavan, Robert Timmerman, Benjamin Chen, John D. Minna, and Timothy D. Solberg , Radiation Research , 2010; (174):62-71

DNA Double Strand Break Formation upon UV-Induced Replication Stress Activates ATM and DNA-PKcs Kinases

Hirohiko Yajima, Kyung-Jong Lee, Shichuan Zhang, Junya Kobayashi, and Benjamin P.C. Chen. , J. Molecular Biology , 2008; (385):800-10