Michael Story, PhD

Associate Professor
Radiation Oncology
Graduate Program: Cancer Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-7600

michael.story@utsouthwestern.edu

Education

Graduate SchoolColorado State University (1989)

Research Interests

Carcinogenesis associated with HZE particle exposure
Intrinsic radiosensitivity
Modulation of drug and radiation response by GSTO expression
molecular markers of radioresponse
Radiotherapy research: SBRT and other

Publications

Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of GSTO1 (p28). .

Giri, U., Terry, N. H. A., Story, M.D. , Cancer Chemother Pharmacol , 2005; (55):511-521

Adenoviral-mediated mda-7 expression suppresses DNA repair capacity and radiosensitizes non-small cell lung cancer cells.

Nishikawa, T., Munshi, A., Story, M.D., Ismail, S., Stevens, C., Chada, S., and Meyn, R.E. , Oncogene , 2004; (23):7125-7131

A Ser49Cys variant in the ataxia telangiectasia, mutated (ATM) gene that is more common in breast cancer patients compared to population controls.

Buchholz, T. A., Weil, M. M., Ashorn, C. L., Strom, E. A., Sigurdson, A., Bondy, M., Chakraborty, R., Cox, J. D., McNeese, M. D., and Story, M.D. , Cancer , 2004; (100):1345-1351

Predicting radiosensitivity using DNA end-binding complex analysis.

Ismail, S.M., Puppi, M., Prithivirasingh, S., Raju, U., Meyn, R. E., Buchholz, T. A., Story, M.D., Brock, W.A., Milas, M., Thames, H. D., and Stevens, C.W. , Clin. Cancer Res. , 2004; (10):1226-1234

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.

Zhang, X, Succi, J, Feng, Z, Prithivirajsingh, S, Story, M.D. and Legerski, R.J. , Molec. Cell Biol , 2004; (24):9207-9220

Honors/Awards

NCI Predoctoral Trainee

(1983)

Professional Associations/Affiliations

American Association for Cancer Research

Federation of American Societies for Experimental Biology

Radiation Research Society