Shuxin Li, MD, PhD

Assistant Professor
Neurology and Neurotherapeutics
Graduate Program: Neuroscience

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

shuxin.li@utsouthwestern.edu

Education

Graduate SchoolOttawa University (2000)
Graduate SchoolHenan Medical University (1989)
Graduate SchoolHenan Medical University, Medicine (1986)

Research Interests

Axonal regeneration in the central nervous system
Cell death and neuronal survival
Spinal cord injury

Publications

Featured
Blockade of Nogo-66, MAG plus OMgp by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.

Li S, Liu BP, Budel S, Li M, Ji B, Walus L, Jirik A, Rabacchi S, Choi E, Worley D, Sah DWY, Pepinsky B, Lee D, Relton J and Strittmatter SM. , Journal of Neuroscience , 2004; (24):10511-10520

Featured
Axon Regeneration in young adult mice lacking Nogo-A/B.

Kim JK*, Li S*, GrandPre T, Qiu K, Greer CA and Strittmatter SM (*Co-first author) , Neuron , 2003; (38):187-199

Featured
Delayed systemic Nogo-66 receptor antagonist after spinal cord injury promotes recovery.

Li S and Strittmatter SM , J Neurosci , 2003; (23:):4219-4227

Featured
Nogo-66 receptor antagonist peptide promotes axonal regeneration.

GrandPre T*, Li S* and Strittmatter SM (*Co-first author) , Nature , 2002; (417):547-551

Featured
Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter.

Li S and Stys PK. , J Neurosci , 2000; (20):1190-98

Inactivation of glycogen synthase kinase-3 promotes axonal growth and recovery in the CNS.

Dill J, Wang H, Zhou FQ and Li S. , J Neurosci , September 2008; (28):8914-28

Nonsteroidal Anti-Inflammatory Drugs Promote Axon Regeneration via RhoA Inhibition.

Fu Q, Hue J and Li S. , J Neurosci , April 2007; (27):4154-64

A Molecular Mechanism for Ibuprofen-mediated RhoA Inhibition in Neurons.

Dill J, Patal AR, Yang X, Bachoo R, Powell CM and Li S. , J Neurosci. , 2010; (30):963-72

Functional axonal regeneration through astrocytic scar genetically modified to digest chondroitin sulfate proteoglycans.

Cafferty W, Yang S, Duffy P, Li S and Strittmatter SM. , J Neurosci , 2007; (27):2176-85

Lack of enhanced spinal regeneration in Nogo deficient mice.

Zheng B, .Ho C, .Li S, Keirstead H, Steward O, Tessier-Lavigne M. , Neuron , 2003; (38):213-224

Honors/Awards

21st National Neurotrauma Society Award, Biloxi

(2003)

Christopher Reeve Paralysis Foundation Award, USA

(2002)

17th National Neurotrauma Society Award, Miami

(1999)

Natural Sciences and Engineering Research Council of Canada Scholarship

(1998)