Xiankai Sun, PhD

Assistant Professor
Radiology, Advanced Imaging Research Center
Graduate Program: Biomedical Engineering

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-8018
Office Fax: 214-648-2678

xiankai.sun@utsouthwestern.edu

Biography

EDUCATION

1995-2000 PhD in Chemistry, University of New Hampshire

2000-2003 Postdoctoral Fellow in Radiopharmaceutical Chemistry, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO

 

POSITIONS AND EMPLOYMENT

2003-2004 Instructor, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO

2004-present Assistant Professor, Department of Radiology & Advanced Imaging Research Center, UT Southwestern

 

 HONORS

1998 Gloria and Robert Lyle Award, University of New Hampshire

2005 Society of Nuclear Medicine Pilot Research Award

 

PROFESSIONAL ACTIVITIES:

1997-present Member, American Chemical Society (ACS)

2000-present Member, American Association of the Advancement of Science

2001-present Member, The Society of Nuclear Medicine

Education

Graduate SchoolUniversity of New Hampshire-Main Campus (2000)

Research Interests

Design and synthesis of novel imaging probes for cancer and diabetes
Developing multimodality imaging methods to noninvasively and longitudinally monitor drug delivery and treatment efficacy

Publications

Featured
Imparting Multivalency to a Bifunctional Chelator: A Scaffold Design for Targeted PET Imaging Probes

Liu W, Hao G, Long LA, Anthony T, Hsieh J-T, and Sun X , Angew. Chem. Int. Ed. , 2009; (48(40)):7346-7349

Featured
The Role of the Size and Number of Polyethylene Glycol Chains in the Biodistribution and Tumor Localization of Triazine Dendrimers

Lim J, Guo Y, Rostollan CL, Stanfield J, Hsieh J-T, Sun X*, and Simanek EE* , Molecular Pharmaceutics , 2008; (5(4)):540-547

Featured
Radiolabeling and In Vivo Behavior of Copper-64-Labeled Cross-Bridged Cyclam Ligands

Sun X, Wuest M, Weisman GR, Wong EH, Reed DP, Motekaitis R, Martell AE, Welch MJ, Anderson CJ , J. Med. Chem. , 2002; (45(2)):469-477

Featured
Rational Design and Assembly of M2M’3L6 Supramolecular Clusters with C3h Symmetry by Exploiting Incommensurate Symmetry Numbers

Sun X, Johnson DW, Caulder DL, Raymond KN, Wong EH , J. Am. Chem. Soc. , 2001; (123):2752-2763

Featured
Exploiting Incommensurate Symmetry Numbers: Rational Design and Assembly of M2M’3L6 Supramolecular Clusters with C3h Symmetry

Sun X, Johnson DW, Caulder DL, Powers RE, Raymond KN, Wong EH , Angew. Chem. Int., Ed. , 1999; (38(9)):1303-1307

A cell permeable peptide analog as a potential specific PET imaging probe for prostate cancer detection

Hao G, Zhou J, Guo Y, Long MA, Anthony T, Stanfield J, Hsieh, J-T, and Sun X , Amino Acids , 2010; (In press)

Gold Nanotags for Combined Multi-Colored Raman Spectroscopy and X-Ray Computed Tomography

Xiao M, Nyagilo J, Arora V, Kulkarni P, Xu D, Sun X, and Dave DP , Nanotechnology , 2010; (21(3)):1-8

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, Long M, Kabbani W, Yu L, Zhang H, Chen H, Sun X, Boothman DA, Min W, and Hsieh JT , Proceedings of the National Academy of Sciences of the United States of America , 2010; (107(6)):2485-2490

Retention of the radiotracers 64Cu-ATSM and 64Cu-PTSM in human and murine tumors is influenced by MDR1 protein expression

Liu J, Hajibeigi A, Ren G, Lin M, Siyambalapitiyage W, Liu Z, Simpson E, Parkey RW, Sun X, and Oz OK , Journal of Nuclear Medicine , 2009; (50(8)):1332-1339

Design, Synthesis, Characterization, and Biodistribution of Triazine Dendrimers Bearing Paclitaxel linked by Ester and Ester/Disulfide Linkages

Lim J, Abdellatif Chouai A, Su-Tang Lo S-T, Liu W, Sun X, and Simanek EE , Bioconjugate Chemistry , 2009; (20(11)):2154-2161