Igor Butovich, PhD

Associate Professor
Ophthalmology
Graduate Program: Biological Chemistry
Download Curriculum Vitae

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-3523
Office Fax: 214-648-9061

igor.butovich@utsouthwestern.edu

Education

Graduate SchoolInst.Of Phys.Chem.Nat. Acad. of Sciences, Kiev, Uk, Chemistry (1985)

Research Interests

Analytical (Bio)Chemistry
Chemistry, Biochemistry, and Biophysics of Lipids
Chemistry, Biochemistry, and Biophysics of Tear Film and Meibum
Drug Discovery
Enzymology

Publications

Featured
Lipidomic Analysis of Human Meibum Using HPLC-MS(n)

I. A. Butovich , Methods in Molecular Biology. Lipidomics , October 2009; (579):221-246

Featured
The Meibomian Puzzle: Combining pieces together

I. A. Butovich , Progress in Retinal and Eye Research , November 2009; (28(6)):483-498

Featured
On the structure and synthesis of neuroprotectin D1, a novel anti-inflammatory compound of the docosahexaenoic family

I. A. Butovich , Journal of Lipid Research , November 2005; (46(11)):2311-2314

Featured
Lipidomics of human meibomian gland secretions: Chemistry, biophysics, and physiological role of meibomian lipids

I. A. Butovich , Progress in Lipid Research , July 2011; (50(3)):278-301

Featured
On the interfacial phenomena in lipoxygenase catalysis

I. A. Butovich, O. V. Kharchenko, V. M. Babenko , Adv. Prostagland. Thromb. Leuk. Res. , 1995; (23):159-161

Meibomian lipid films and the impact of temperature

I. A. Butovich, J. C. Arciniega, J. C. Wojtowicz , Invest. Ophthalmol. Vis. Sci. , November 2010; (51(11)):5508-5518

Cholesteryl esters as a depot for very long chain fatty acids in human meibum

I. A. Butovich , Journal of Lipid Research , March 2009; (50(3)):501-513

Comparative HPLC-MS(n) analysis of canine and human meibomian lipidomes: Many similarities, a few differences

I. A. Butovich, A. M. Borowiak, J. C. Eule , Scientific Reports , June 2011; (1:24):1-12

Human tear film and meibum. I. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum

I. A. Butovich, J. C. Wojtowicz, M. Molai , Journal of Lipid Research , December 2009; (50(12)):2471-2485

Effects of free fatty acids on meibomian lipid films

J. C. Arciniega, E. J. Nadji, I. A. Butovich , Experimental Eye Research , 2011; (In press)

Honors/Awards

Lipids and Proteins Committee member

Tear Film and Ocular Surface Society (2011)

Int’l. Advisory Board member

Second and Third Int’l. Conference on Drug Discovery & Therapy, Dubai, UAE (2010)

The Royal Society of Medicine, London, United Kingdom

Overseas Fellow (2010)

National Academy of Sciences, Ukraine

Senior Research Fellow, Bioorganic Chemistry (1997)

3 NIH R01 research awards

3R01EY01948-01A1S1; 5R01EY019480-02; 1R01EY019480-01A1

Professional Associations/Affiliations

Tear Film and Ocular Surface Society (TFOS, USA, since 2005)

The Association for Research in Vision and Ophthalmology (ARVO, USA, since 2005)

The Royal Society of Medicine (RSM, United Kingdom, since 2010)