Chaitanya Nirodi, PhD

Assistant Professor
Radiation Oncology
Graduate Program: Cancer Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-7600

chaitanya.nirodi@utsouthwestern.edu

Education

Graduate SchoolVanderbilt University (1995)

Research Interests

Mechanisms of resistance to radiation-induced cell death
Radiosensitivity associated with somatic, activating mutations in the EGFR gene in non-small cell lung cancer harboring spontaneous
Role of epiderma growth factor in tumorigenesis and radiation resistance

Publications

Non-Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation

Das, A.K., Sato, M., Story, M.D., Peyton, M., Graves, R.G., Redpath, S., Griard. L., Gazdar, A.F., Shay, Minna, J.D. and Nirodi, C.S , Cancer Research , October 2006; (66 (19)):9601-9608

The Epidermal Growth Factor Receptor: A Role in Repair of Radiation-induced DNA damage

David J. Chen and Chaitanya Nirodi , Clinical Cancer Research , November 2007; (13 (22)):6555-6560

Somatic Mutations in the Tyrosine Kinase Domain of EGFR abrogate EGFR-mediated Radio-protection in Non-Small Cell Lung Carcinoma

Amit K. Das, Mitsuo Sato, Michael Peyton, Benjamin P. Chen, David J. Chen, Michael D. Story, John C. Minna and Chaitanya S. Nirodi. , Cancer Research , June 2007; (67 (11)):5267-5374

The role of CDP in the negative regulation of CXCL1 gene expression

Nirodi C, Hart J, Dhawan P, Moon NS, Nepveu A, Richmond A. , Journal of Biological Chemistry , July 2001; (276(28)):26122-31

The Glyceryl prostaglandin, PGE2-G mobilizes calcium in RAW 264.7 cells

Nirodi, C.S., Crews, B., Kozak, K., and Marnett, L. , Proc.Natl.Acad.Science, , February 2004; (101(7)):1840-45

Honors/Awards

Senior Research Fellowship Grant, Center for Scientific and Industrial Research, India

(1989)

Indian Institute of Science Merit Scholarship for Academic Research

(1988)

Junior Research Fellowship Grant, University Grants Commission, India

(1988)