Tianfu Wu, PhD

Assistant Professor
Internal Medicine
Download Curriculum Vitae

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

tianfu.wu@utsouthwestern.edu

Education

Graduate SchoolInstitute of Hydrobiology, Cas, China, Biology (1999)

Research Interests

Discovery of early biomarkers for lupus and lupus nephritis.
Signaling transduction pathways of lupus and lupus nephritis.
Target and inhibitors of lupus and lupus nephritis

Publications

Featured
Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus.

Wu T, Qin X, Kurepa Z, Kumar KR, Liu K, Kanta H, Zhou XJ, Satterthwaite AB, Davis LS, Mohan C. , J Clin Invest. 2007 Jul 19; [Epub ahead of print] , July 2007; (117)

Featured
Urine proteome scans uncover total urinary protease, prostaglandin d synthase, serum amyloid p, and superoxide dismutase as potential markers of lupus nephritis.

Wu T, Fu Y, Brekken D, Yan M, Zhou XJ, Vanarsa K, Deljavan N, Ahn C, Putterman C, Mohan C. , J Immunol. , February 2010; (184(4):):2183-93

Featured
Excreted Urinary Mediators in Immune Nephritis with Potential Pathogenic Significance

Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen SS, Zhou XJ, Putterman C, Mohan C. , Arthritis & Rheumatism , 2007; (56(3)):949-959

Featured
Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis.

Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C. , J Immunol. , 2007; (179(10):):7166-75.

Featured
Glomerular Proteome Arrays -- A Novel Approach to Uncover Autoantibody Clusters that best Predict Disease Activity in Lupus

Li QZ, Xie C, Wu T, Mackay M, Aranow C, Putterman C, Mohan C. , The Journal of Clinical Investigation , 2005; (115(12)):3428-3439

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice.

Santiago-Raber ML, Dunand-Sauthier I, Wu T, Li QZ, Uematsu S, Akira S, Reith W, Mohan C, Kotzin BL, Izui S. , J Autoimmun , November 2009;

Proteomic toolbox for autoimmunity research.

Wu T, Mohan C. , Autoimmun Rev. , June 2009; (8(7)):595-8.

The AKT axis as a therapeutic target in autoimmune diseases.

Wu T, Mohan C. , Endocr Metab Immune Disord Drug Targets , June 2009; (9(2):):145-50

Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity.

Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK 3rd, Wu T, Li QZ, Davis LS, Mohan C, Perlman H. , Immunity. , February 2008; (28(2):):206-17.

Honors/Awards

Pilot Award

Alliance for Lupus Research (2007)

Travel Award for AACR Annual meeting

Novartis (2006)

Best Paper Award

Chinese Society of Oceanology & Limnology (2001)

Scholarship

Max-Planck-Society (2001)

Best Paper Award

Chinese Society of Oceanology & Limnology (1999)

National Marine 863 Initiatives Award

Chinese Ministry of Science & Technology (1999)

Di-Ao Award

Chinese Academy of Sciences (1998)

Professional Associations/Affiliations

American Heart Association (AHA)

(2012)

Association of Rheumatology Health Professionals (ARHP)

(2011)

American Association for Cancer Research (AACR)

(2004)