Olaf Stuve, MD, PhD

Associate Professor
Neurology and Neurotherapeutics
Graduate Program: Immunology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

olaf.stuve@utsouthwestern.edu

Biography

BIRTHDATE: May 5, 1964

BIRTHPLACE: Dusseldorf, Germany

CIVIL STATUS: Married

LANGUAGES: English, German, and Spanish

CURRENT POSITION:

Associate Professor, Department of Neurology, UT Southwestern, 12/2004 – present

 Staff physician, Neurology Section, VA North Texas Health Care Systems, Medical Service, 07/2005 - present

 

PROFESSIONAL EXPERIENCE

Assistant Professor, Department of Neurology, Heinrich Heine University Dusseldorf, 10/2003-05/2005

 

MEDICAL EDUCATION

MD: Free University of Berlin Medical School, Germany, 1993

MD Thesis: Max Delbruck Center for Molecular Medicine, Department of Hypertension, Nephrology and Genetics, Free University of Berlin, Germany, 1994

PhD: Department of Clinical and Experimental Immunology, University of Maastricht, The Netherlands, 2006

Internship Surgery Transitional Internship, Groote Schuur Hospital, University of Cape Town, South Africa, 1994

Internal Medicine Preliminary Internship, University of Washington, Seattle 1996-1997

Residency Neurology, University of Washington, Seattle, 1997-2000

 

POSTDOCTORAL FELLOWSHIPS

Neuroimmunology, Montreal Neurological Institute, McGill University, Montreal, 1994-1996

Neuroimmunology, University of California, San Francisco, 2000 - 2003 Licensure California medical license (active, No. A75979), 2001

Texas medical license (active, No. M0936), 2005

Washington State medical license (active, No. MD00039298), 2000

German medical license (active) 1995

South African limited registration (inactive) 1993

Board Certification Board Certified by the American Board of Psychiatry and Neurology (active, No. 52130), 2003

 

SOCIETY MEMBERSHIP

Alumni Club of the Charite (ACDC), Humboldt-University Berlin, 2005 - present

American Academy of Neurology (AAN), 1995 - present

American Association for the Advancement of Science (AAAS), 1999 - present

American Association of Immunologists (AAI), 1999 - present

American Medical Association (AMA), 2000 - present Clinical Immunology Society (CIS), 2003 - present

Dallas County Medical Society (DCMS), 2005 - present

International Association of Obituarists (IAO), 2003 - present

International Society of Neuroimmunology (ISNI), 2004 - present

Texas Medical Association (TMA), 2005 - present

The Berlin Society of Psychiatry and Neurology (BGPN), 2006 - present

National Scientific Committee Membership National Multiple Sclerosis Society (NMSS) Scientific Advisory Committee, Lone Star Chapter, 2004 - present

 

OTHER

High school exchange student with the American Field Service (AFS), Instituto Salesiano San Miguel, Tegucigalpa, Honduras, 1981-1982

Military Service, Cologne, Germany, 1984-1986            

 

Education

Graduate SchoolMax-Delbruck-Centrum for Molecular (1994)
Graduate SchoolMax-Delbruck-Centrum for Molecular (1994)
Graduate SchoolFree University, Berlin, Germany (1993)

Research Interests

Peroxisome proliferator-activated receptor agonists as treatment for autoimmune demyelination
T cell activation requirement in autoimmune demyelination
The role of prion protein as a disease modifier in autoimmune diseases of the central nervous system
The role of prion protein as a disease modifier in autoimmune diseases of the central nervous system
The role of prion protein as a disease modifier in autoimmune diseases of the central nervous system

Publications

Featured
Altered CD4+/CD8+ T cells ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis

Stuve O, Marra CM, Bar-Or A, Niino M, Cravens PD, Cepok S, Frohman EM, Phillips JT, Arendt G, Jerome KR, Cook L, Grand’Maison F, Hemmer B, Monson NL, Racke MK , Archives of Neurology , 2006; (63):1383-1387

Featured
Immune surveillance in multiple sclerosis patients treated with natalizumab

Stuve O, Marra CM, Jerome KR, Cook L, Cravens PD, Cepok S, Frohman EM, Phillips JT, Arendt G, Hemmer B, Monson NL, Racke MK , Annals of Neurology , 2006; (59):743-747

Featured
Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

Stuve O, Youssef S, Weber MS, Nessler S, von Budingen H-C, Hemmer B, Sobel RA, Steinman L, Zamvil SS , Journal of Clinical Investigation , 2006; (116):1037-1044

Featured
Natalizumab decreases the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces

Martin MdelP, Cravens PD, Winger R, Frohman EM, Racke MK, Eagar TN, Monson NL, Zamvil SS, Weber MS, Hemmer B, Karandikar NJ, Kleinschmidt-DeMasters BK, Stuve O , Archives of Neurology , ; (In press)

Reactivation of Human Herpesvirus-6 in natalizumab treated multiple sclerosis patients

Yao K, Gagnon S, Akhyani N, Williams E, Fotheringham J, Frohman EM, Stuve O, Monson N, Racke MK, Jacobson S , PLoS ONE , 2008; (30):e2028

Humoral immune responses after rabies infection

Watson NF, Woo D, Doherty MJ, Frohman EM, Racke MK, De Baets M, Hartung H-P, Kieseier BC, Stuve O. , Archives of Neurology , 2007; (64):1355-6

The death domain containing kinase RIP1 regulates p27Kip1 levels via a PI3K-Akt-Forkhead pathway

Park S, Ramnarain DB, Hatanpaa KJ, Mickey BE, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S, Ali MA, Puttaparthi K, Hu W, Elliott JL, Stuve O, Habib AA , EMBO reports , ; (In press)

Natalizumab decreases the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces

Martin MdelP, Cravens PD, Winger R, Frohman EM, Racke MK, Eagar TN, Monson NL, Zamvil SS, Weber MS, Hemmer B, Karandikar NJ, Kleinschmidt-DeMasters BK, Stuve O , Archives of Neurology , ; (In press)

Immunological and clinical status 14 months after cessation of natalizumab therapy

Stuve O, Cravens PD, Frohman EM, Phillips JT, Remington GM, von Geldern G, Cepok S, Singh MP, Cohen Tervaert JW, De Baets M, MacManus D, Miller DH, Radu EW, Cameron EM, Monson NL, Zhang S, Kim R, Hemmer B, Racke MK , Neurology , ; (In press)