Victor Babich, PhD

Instructor
Internal Medicine

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

victor.babich@utsouthwestern.edu

Education

Graduate SchoolRussian Academy of Sciences - Russia, Molecular Biology (2000)
Graduate SchoolSt. Petersburg Techical Institute - Russia, Physics (1997)

Research Interests

Molecular Biophysics of Ion Transport
Regulation of Endo- and Exo-cytosis

Publications

Featured
Differential effect of extracellular acidosis on the release and dispersal of soluble and membrane proteins secreted from the Weibel-Palade body.

V Babich, L Knipe, L Hewlett, A Meli, J Dempster , MJ Hannah, T Carter , J Biol Chem , May 2009; (284(18)):12459-68

Featured
Selective release of molecules from Weibel-Palade bodies during a lingering kiss

V Babich, A Meli, L Knipe , JE Dempster, P Skehel, MJ Hannah, T Carter , Blood , June 2008; (111(11)):5282-90

Featured
Clusters of regulatory signals for RNA polymerase II transcription associated with Alu family repeats and CpG islands in human promoters

SL Oei, VS Babich, Vl Kazakov, NM Usmanova, AV Kropotov, NV Tomilin , Genomics , 2004; (83):873-882

Featured
The N-terminal extracellular domain is required for polycystin-1-dependent channel activity.

V Babich, WZ Zeng, BI Yeh, O Ibraghimov-Beskrovnaya, Y Cai, S Somlo, CL Huang , J Biol Chem , 2004; (279):25582-25589

Featured
Association of some potential hormone response elements in human genes with the Alu family repeats

V Babich, N Aksenov, V Alexeenko, SL Oei, G Buchlow, N Tomilin , Gene , 1999; (239):341-349

Differential effect of extracellular acidosis on the release and dispersal of soluble and membrane proteins secreted from the Weibel-Palade body.

V Babich, L Knipe, L Hewlett, A Meli, J Dempster, MJ Hannah, T Carter , J Biol Chem , May 2009; (284(18)):12459-68

Selective release of molecules from Weibel-Palade bodies during a lingering kiss.

V Babich, A Meli, L Knipe, JE Dempster, P Skehel, MJ Hannah, T Carter , Blood , June 2008; (111(11)):5282-90

Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells

F Di Sole, R Cerull, V Babich, V Casavola, C Helmle-Roth, G Burckhardt , J Cell Physiol , July 2008; (216(1)):221-33

The calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylation.

F Di Sole, V Babich, OW Moe , J Am Soc Nephrol , August 2009; (20(8)):1776-86

Rate, extent and concentration dependence of histamine-evoked Weibel-Palade body exocytosis determined from individual fusion events in human endothelial cells

M Erent, A Meli, N Moisoi, V Babich, MJ Hannah, P Skehel, L Knipe, G Zupancic, D Ogden, T Carter , J Physiol , August 2007; (Pt 1/583):195-212

Honors/Awards

UT Southwestern Graduate School of Biomedical Sciences

Haberecht Wildhare-Idea Research Award (2009)

St. Petersburg Government

Research Fellowship (1998)

St. Petersburg Government

Research Fellowship (1996)

Professional Associations/Affiliations

American Society of Nephrology

Biophysical Society