Search For Faculty
Are You a Faculty Member?
If you are a faculty member and would like to make a change to your faculty profile, please login to Profile+ with your UT Southwestern Id and password. Questions? Please email Web Services at webservices@utsouthwestern.edu.

David Self, PhD
Endowed Title: Wesley Gilliland Professorship in Biomedical Research
Contact Information
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390
Office Phone: 214-648-1237
Office Fax: 214-648-4947
Biography
Dr. Self received his bachelor’s in Zoology from Iowa State University in 1985, and worked as a biochemist at Endocrine Sciences in Los Angeles, CA until 1987. Dr. Self entered graduate school in 1987 in the Department of Pharmacology at UC Irvine, and received a PhD there in 1992. Dr. Self was a postdoctoral fellow from 1992-1995 in the Division of Molecular Psychiatry at Yale University. Dr. Self was appointed to an Assistant Professorship in the Psychiatry Department at Yale University in 1996.
In late 2000, Dr. Self joined the UT Southwestern faculty as an Associate Professor of Psychiatry in the Seay Center for Basic and Applied Research in Psychiatric Illness. Dr. Self has pioneered work on the role of neuroadaptations in addictive behavior, and has identified important neurobiological mechanisms underlying drug craving and relapse to drug seeking. In 1996, he was awarded a Presidential Early Career Award by the White House, and in 2007, the prestigious Daniel H. Efron Award by the American College of Neuropsychopharmacology, for contributions relating to this work. His laboratory continues to implement modern molecular technology in the study of addictive behavior.
Education
| Graduate School | University of California-Irvine (1992) |
| Undergraduate | Iowa State University (1985) |
Research Interests
Publications
Self, D.W. , Biological Psychiatry , 2005; (57):1479-1484
Self, D.W. Choi, K-H., Simmons, D., Walker, J.R. and Smagula, C.S. , Learning and Memory , 2004; (11):648-657
Colby, C.R., Whisler, K., Steffen, C., Nestler, E.J., Self, D.W. , J. Neurosci. , 2003; (23):2488-2493
Sutton, M.A., Schmidt, E.F., Choi, K-H., Schad, C.A., Whisler, K., Simmons, D., Karanian, D.A., Monteggia, L.M., Neve, R.L. and Self, D.W. , Nature , 2003; (421):70-75
Self, D.W., Barnhart, W.J., Lehman, D.A. and Nestler, E.J. , Science , 1996; (271):1586-1589
Graham, D.L., Krishnan, V., Larson, E.B., Graham, A., Edwards, S., Bachtell, R.K., Simmons, D., Gent, L.M., Berton, O., Bolanos, C.A., DiLeone, R.J., Parada, L.F., Nestler, E.J. and Self, D.W. , Biological Psychiatry , 2009; (65):896-901
Bachtell, R.K., Choi, K-H., Monteggia, L.M., Neve, R. L. and Self, D.W. , European Journal of Neuroscience , 2008; (27):2229-2240
Graham, D.L., Edwards, S., Bachtell, R.K., DiLeone, R.J, Rios, M. and Self, D.W. , Nature Neuroscience , 2007; (10):1029-1037
Edwards, S., Whisler, K.N., Fuller. D.C., Orsulak, P.J. and Self, D.W. , Neuropsychopharmacology , 2007; (32):354-366
Edwards, S., Graham, D.L., Bachtell, R.K. and Self, D.W. , Eur. J. Neurosci , 2007; (25):2201-2213
Related Links
Honors/Awards
American College of Neuropsychopharmacology (2006)
American College of Neuropsychopharmacology (2003)
Dept. of Psychiatry. UT Southwestern Medical Center (2001)
Awarded by the White House for "Innovative integration of molecular biology with behavioral, pharmacological and biochemical techniques in the study of drug addiction" (1996)