Dominika Borek, Ph.D.

Graduate School

Adam Mickiewicz University-Pol (1997), Chemistry

Graduate School

Adam Mickiewicz University-Pol (2001), Physical Chemistry

Graduate School

Univ of London-Uni College (2001), Structural Biology

• chromatin structure
• evolution
• next generation sequencing
• structural biology

Featured Publications

Diffraction data analysis in the presence of radiation damage.

Borek D, Cymborowski M, Machius M, Minor W, Otwinowski Z Acta Crystallogr. D Biol. Crystallogr. 2010 Apr 66 Pt 4 426-36

The many faces of radiation-induced changes.

Borek D, Ginell SL, Cymborowski M, Minor W, Otwinowski Z J Synchrotron Radiat 2007 Jan 14 Pt 1 24-33

Expression, purification and catalytic activity of Lupinus luteus asparagine beta-amidohydrolase and its Escherichia coli homolog.

Borek D, Michalska K, Brzezinski K, Kisiel A, Podkowinski J, Bonthron DT, Krowarsch D, Otlewski J, Jaskolski M Eur. J. Biochem. 2004 Aug 271 15 3215-26

Measurement errors and their consequences in protein crystallography.

Borek D, Minor W, Otwinowski Z Acta Crystallogr. D Biol. Crystallogr. 2003 Nov 59 Pt 11 2031-8

Multiparametric scaling of diffraction intensities.

Otwinowski Z, Borek D, Majewski W, Minor W Acta Crystallogr., A, Found. Crystallogr. 2003 May 59 Pt 3 228-34

Crystal Structure of Cardiac Troponin C Regulatory Domain in Complex with Cadmium and Deoxycholic Acid Reveals Novel Conformation.

Li AY, Lee J, Borek D, Otwinowski Z, Tibbits GF, Paetzel M Journal of molecular biology 2011 Sep

Structure and control of the actin regulatory WAVE complex.

Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK Nature 2010 Nov 468 7323 533-8

To automate or not to automate: this is the question.

Cymborowski M, Klimecka M, Chruszcz M, Zimmerman MD, Shumilin IA, Borek D, Lazarski K, Joachimiak A, Otwinowski Z, Anderson W, Minor W J. Struct. Funct. Genomics 2010 Sep 11 3 211-21

Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain.

Leung DW, Shabman RS, Farahbakhsh M, Prins KC, Borek DM, Wang T, Mühlberger E, Basler CF, Amarasinghe GK J. Mol. Biol. 2010 Jun 399 3 347-57

Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins.

Leung DW, Borek D, Farahbakhsh M, Ramanan P, Nix JC, Wang T, Prins KC, Otwinowski Z, Honzatko RB, Helgeson LA, Basler CF, Amarasinghe GK Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2010 Jun 66 Pt 6 689-92

• NARSAD Young Investigator Award
  (2005)

• American Crystallographic Association