Wen-Hong Li, PhD

Associate Professor
Endowed Title: Southwestern Medical Foundation Scholar in Medical Research 2000-2004
Cell Biology, Biochemistry
Graduate Program: Biological Chemistry
Biomedical Engineering

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-6362
Office Fax: 214-648-6839

wen-hong.li@utsouthwestern.edu

Education

Graduate SchoolUniversity of California-San Diego (1996)
Graduate SchoolUniversity of California-San Diego (1993)

Research Interests

Cell biology of diabetes and insulin release in islet beta cells
Functional analysis of microRNAs
Probe engineering and chemical biology

Publications

Featured
Temporal and Spatial Regulation of MicroRNA Activity with Photoactivatable Cantimirs.

Zheng G, Cochella L, Liu J, Hobert O, Li WH, ACS chemical biology, 2011 Dec; 6 (12):1332-8

Featured
Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR).

Li D, Chen S, Bellomo EA, Tarasov AI, Kaut C, Rutter GA, Li WH, Proceedings of the National Academy of Sciences of the United States of America, 2011 Dec;

Featured
Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMP

Yan-Ming Guo, Shiuhwei Chen, Premnath Shetty, Genhua Zheng, Rueyling Lin, Wen-hong Li , Nature Methods , 2008; (5):835-841

Featured
LAMP, A New Imaging Assay of Gap Junctional Communication Unveils That Ca2+ Influx Inhibits Cell Coupling

Kenneth Dakin, YuRui Zhao & Wen-hong Li , Nature Methods , 2005; (2):55-62 (News & Views, 12-14)

Cell Membrane Permeable Esters of D-myo-Inositol 1,4,5-Trisphosphate

Kenneth Dakin & Wen-hong Li , Cell Calcium , 2007; (42):291-301

Photoactivatable and Water Soluble FRET Dyes with High Uncaging Cross Section

Genghua Zheng, Yan-Ming Guo & Wen-hong Li , J. Am. Chem. Soc. , 2007; (129):10616-10617

Local Ca2+ Rise Near Store Operated Ca2+ Channels Inhibits Cell Coupling During Capacitative Ca2+ Influx

Kenneth Dakin & Wen-hong Li , Cell Commun. Adhes. , 2006; (13):29-39

Infrared LAMP, Two-Photon Uncaging and Imaging of Gap Junctional Communication in Three Dimensions

Kenneth Dakin & Wen-hong Li , Nature Methods , 2006; (3):959

A New Class of Macrocyclic Lanthanide Complexes for Cell Labeling and Magnetic Resonance Imaging Applications

Quan Zheng, Houquan Dai, Matthew E. Merritt, Craig Malloy, CaiYuan Pan & Wen-hong Li , J . Am. Chem. Soc. , 2005; (127):16178-16188

Honors/Awards

Junior Investigator Award

American Cancer Society (2002)

Career Development Award

American Diabetes Associaiton (2001)

Martin D. Karmen Prize

In recognition of the excellence of Ph.D. thesis, UCSD (1997)

Jane Hart Memorial Award

Department of Chemistry and Biochemistry, University of California, San Diego (1994)

Professional Associations/Affiliations

The American Diabetes Association

(2006)

The American Chemical Society

The American Society for Cell Biology