Ege Kavalali, PhD

Professor
Endowed Title: Effie Marie Cain Scholar in Medical Research 1999-2003
Rosewood Corporation Chair in Biomedical Science
Neuroscience, Physiology
Graduate Program: Molecular Biophysics
Neuroscience

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-1800
Office Fax: 214-648-1801

ege.kavalali@utsouthwestern.edu

Biography

As an undergraduate. Dr. Kavalali studied Electrical Engineering at Bogazici University in Istanbul, Turkey. In 1995, he completed his PhD in Rutgers University, where he worked with Dr. Mark Plummer. He joined the then-Center for Basic Neuroscience in September 1999, following completion of his postdoctoral studies with Dr. Richard W. Tsien in Stanford University at the Department of Molecular and Cellular Physiology.

Education

Graduate SchoolRutgers University New Brunswick (1995)
UndergraduateBpgazici University (1990)

Research Interests

Electrophysiology
Neurodevelopmental Disorders
Synaptic Plasticity
Synaptic Transmission

Publications

Featured
Spontaneous and evoked glutamate release activates two populations of NMDA receptors with limited overlap

Atasoy D, Ertunc M, Moulder KL, Blackwell J, Chung C, Su J, Kavalali ET , The Journal of Neuroscience , 2008; (28):10151-10166

Featured
Selective capability of SynCAM and Neuroligin for functional synapse assembly

Sara Y, Biederer T, Atasoy D, Chubykin A, Mozhayeva MG, Sudhof TC, Kavalali ET , The Journal of Neuroscience , 2005; (25):260-270

Featured
An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission

Sara Y, Virmani T, Deak F, Liu X, Kavalali ET , Neuron , 2005; (45):563-573

Featured
Synaptobrevin is essential for fast synaptic vesicle endocytosis

Deak F, Schoch S, Liu X, Sudhof TC, Kavalali ET , Nature Cell Biology , 2004; (6):1102-1108

Featured
SNARE function analyzed in synaptobrevin/VAMP knockout mice

Schoch S, Deak F, Konigstorfer A, Mozhayeva M, Sara Y, Sudhof TC, Kavalali ET , Science , 2001; (294):1117-1122

Spontaneous and evoked glutamate release activates two populations of NMDA receptors with limited overlap

Atasoy D, Ertunc M, Moulder KL, Blackwell J, Chung C, Su J, Kavalali ET , The Journal of Neuroscience , 2008; (28):10151-10166

Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling

Wasser C, Ertunc M, Liu X, Kavalali ET , The Journal of Physiology (Lond.) , 2007; (579):413-429

Activity-dependent validation of excitatory versus inhibitory synapses by Neuroligin-1 versus Neuroligin-2

Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Sudhof TC , Neuron , 2007; (54):919-931

Fast synaptic vesicle reuse slows the rate of synaptic depression in the CA1 region of hippocampus

Ertunc M, Sara Y, Chung C, Atasoy D, Virmani T, Kavalali ET , The Journal of Neuroscience , 2007; (27):341-354

MeCP2-dependent transcriptional repression regulates excitatory neurotransmission

Nelson ED, Kavalali ET, Monteggia LM , Current Biology , 2006; (16):710-716

Honors/Awards

American Heart Association Established Investigator Award

(2006)

Effie Marie Cain Scholar in Medical Research

(1999)

American Heart Association Postdoctoral Fellowship

(1996)