Scott Smith, PhD

Associate Professor
Physical Therapy, Internal Medicine
Graduate Program: Biomedical Engineering

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-1551
Office Fax: 214-648-1511

scott.smith@utsouthwestern.edu

Education

Graduate SchoolUniversity of North Texas Health Science Center, Physiology (1999)
Graduate SchoolUniversity of North Texas Health Science Center, Science (1996)
UndergraduateSouthwestern University, Biology (1992)

Research Interests

Neural Cardiovascular Control during Exercise
Reflex Dysfunction in Heart Failure
Reflex Dysfunction in Hypertension

Publications

Featured
Exercise pressor reflex funtion is altered in spontaneously hypertensive rats

SA Smith, MA Williams, AK Leal, JH Mitchell and MG Garry , Journal of Physiology , 2006; (577.3):1009-1020

Featured
The capsaicin sensitive afferent neuron in skeletal muscle is abnormal in heart failure

SA Smith, MA Williams, JH Mitchell, PPA Mammen, MG Garry , Circulation , 2005; (111):2056-2065

Featured
Independent modification of baroreceptor and exercise pressor reflex function by nitric oxide in the nucleus tractus solitarius

SA Smith, JH Mitchell and J Li , American Journal of Physiology , 2005; (288):H2068-H2076

Featured
The role of the exercise pressor reflex in rats with dilated cardiomyopathy

SA Smith, PPA Mammen, JH Mitchell, MG Garry , Circulation , 2003; (108):1126-1132

Featured
Partial blockade of skeletal muscle somatosensory afferents attenuates baroreflex resetting during exercise in humans

SA Smith, RG Querry, PJ Fadel, KM Gallagher, M Stromstad, K Ide, PB Raven and NH Secher , Journal of Physiology , 2003; (551.3):1013-1021

Skeletal muscle reflex-mediated changes in sympathetic nerve activity are abnormal in spontaneously hypertensive rats

M Mizuno, MN Murphy, JH Mitchell and SA Smith , American Journal of Physiology , 2011; ((in press))

The TRPv1 receptor is a mediator of the exercise pressor reflex in rats

SA Smith, AK Leal, MA Williams, MN Murphy, JH Mitchell and MG Garry. , Journal of Physiology , 2010; (599.7):1179-1189

The group IV afferent neuron expresses multiple receptor alterations in cardiomyopathy: evidence at the cannabinoid CB1 receptor

MA Williams, SA Smith, DE O’Brien, JH Mitchell and MG Garry , Journal of Physiology , 2008; (586.3):835-845

Evidence for functional alterations in the skeletal muscle mechanoreflex and metaboreflex in hypertensive rats

AK Leal, MA Williams, MG Garry, JH Mitchell and SA Smith , American Journal of Physiology , 2008; (295):H1429-H1438

The mechanoreflex mediates the exaggerated exercise pressor reflex in heart failure

SA Smith, JH Mitchell, RH Naseem, MG Garry , Circulation , 2005; (112):2293-2300

Honors/Awards

Basic Research Grant (R01)

National Institutes of Health (2008)

Scientist Development Grant

American Heart Association - National (2007)

Beginning Grant-in-Aid

American Heart Association - Texas Affiliate (2005)

New Investigator Award for Excellence in Research

UT Southwestern Allied Health Sciences School (2004)

Young Investigator Award

American Physiological Society Central Nervous System Section (2002)

Professional Associations/Affiliations

American College of Sports Medicine

American Heart Association

American Physiological Society