Lance Terada, MD

Professor
Internal Medicine, Surgery
Graduate Program: Cell Regulation

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

lance.terada@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Education

FellowshipUniversity of Colorado Health Sciences Center (1989)
ResidencyUniversity Hospitals of Cleveland (1986)
Medical SchoolUniversity of Hawaii (1983)

Research Interests

Anchorage sensing and anoikis
Oxidant Biochemistry
Signal Transduction
Vascular Biololgy

Publications

Featured
Specificity in reactive oxidant signaling: Think globally, act locally

Terada, L.S. , J. Cell Biol. , 2006; (174):615-623

Featured
Subcellular targeting of oxidants during endothelial cell migration

Wu, R.F., Y.C. Xu, Z. Ma, F.E. Nwariaku, G.A, Sarosi, and L.S. Terada. , J. Cell Biol. , 2005; (171):893

Featured
VEGF causes translocation of p47phox to membrane ruffles through WAVE1.

Wu, R.F., Y. Gu, Y.C. Xu, F.E. Nwariaku, and L.S. Terada , J. Biol. Chem. , 2003; (278):36830-36840

Featured
p47phox participates in activation of RelA in endothelial cells.

Gu, Y., Y.C. Xu, R.F. Wu, F.E. Nwariaku, R.F. Souza, S.C. Flores, and L.S. Terada. , J. Biol. Chem. , 2003; (278):17210-17217

Featured
Involvement of TRAF4 in oxidative activation of c-Jun amino terminal kinase

Y.C. Xu, R.F. Wu, Y. Gu, Y.S. Yang, M.C. Yang, F.E. Nwariaku, L.S. Terada , J. Biol. Chem , 2002; (277):28051-28057

p66Shc restrains Ras hyperactivation and suppresses metastatic behavior.

Ma, Z., Z. Liu, R.F. Wu, and L.S. Terada. , Oncogene , 2010; (29):5559-5567

Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation.

Wu, R.F., Z. Ma, Z. Liu, and L.S. Terada. , Mol. Cell. Biol. , 2010; (30):3553-3568.

p66Shc mediates anoikis through RhoA

Ma, Z., D.P. Myers, R.F. Wu, F.E. Nwariaku, and L.S. Terada. , J. Cell Biol. , 2007; (179):23

HIV1 Tat activates dual Nox pathways leading to independent activation of ERK and JNK MAP kinases.

Wu, R.F., Z. Ma, D.P. Myers, and L.S. Terada. , J. Biol. Chem. , 2007; (282):37412

Endothelial progenitor cell mobilization after percutaneous coronary intervention

Banerjee, S., E. Brilakis, S. Zhang, M. Roesle, J. Lindsey, B. Philips, C.G. Blewett, and L.S. Terada , Atherosclerosis , 2006; (189):70-75

Honors/Awards

American Heart Association

Established Investigator Award (1996)

Will Rogers Research Fellow

(1988)

Research Competition Award - Case Western Research Univ

(1986)

Alpha Omega Alpha

(1982)

Professional Associations/Affiliations

American Federation for Medical Research

American Physiological Society

American Society for Biochemistry and Molecular Biology

American Thoracic Society