Xiang Luo, MD, PhD

Instructor
Internal Medicine

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

xiang.luo@utsouthwestern.edu

Education

Graduate SchoolTongji Medical University, Medicine (1996)
Graduate SchoolTongji Medical University, Medicine (1992)
Graduate SchoolHengyang Medical College - China, Medicine (1989)

Research Interests

Ca2+ signaling and its transduction pathway
Effects and regulation of ion transport in epithelial cells

Publications

Featured
RGS proteins provide biochemical control of agonist-evoked [Ca2+]i oscillations.

Luo X, Popov S, Bera AK, Wilkie TM, Muallem S , Mol Cell , March 2001; (7(3)):651-60

Featured
Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities.

Shin DM, Dehoff M, Luo X, Kang SH, Tu J, Nayak SK, Ross EM, Worley PF, Muallem S , J Cell Biol , July 2003; (162(2)):293-303

Featured
Multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells.

Luo X, Zheng W, Yan M, Lee MG, Muallem S , Am J Physiol , August 1999; (277(2 Pt 1)):C205-15

Featured
Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice.

Luo X, Shin DM, Wang X, Konieczny SF, Muallem S , J Biol Chem , April 2005; (280(13)):12668-75

Mitochondrial aberrations in mucolipidosis type IV.

Jennings JJ Jr, Zhu JH, Rbaibi Y, Luo X, Chu CT, Kiselyov K , J Biol Chem , October 2006; ([Epub ahead of print])

Regulation of the P2X7 receptor permeability to large molecules by extracellular Cl- and Na+.

Li Q, Luo X, Muallem S , J Biol Chem , July 2005; (280(29)):26922-7

Functional mapping of Ca2+ signaling complexes in plasma membrane microdomains of polarized cells.

Li Q, Luo X, Muallem S , J Biol Chem , July 2004; (279(27)):27837-40

Critical role of PIP5KIγ87 in InsP3-mediated Ca2+ signaling.

Wang YJ, Li WH, Wang J, Xu K, Dong P, Luo X, Yin HL , J Cell Biol , December 2004; (167(6)):1005-10

Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice.

Luo X, Shin DM, Wang X, Konieczny SF, Muallem S , J Biol Chem , April 2005; (280(13)):12668-75

Honors/Awards

1993-1996

Tongji Medical University Scholarship

1995

Prestigious Award for Ph.D. Students, Tongji Medical University

1996

Outstanding Postgraduate Award, Tongji Medical University

1998-2005

Editorial Board, Journal of China Pharmacy

Professional Associations/Affiliations

Federation of American Societies for Experimental Biology

The American Physiologcal Society

The Chinese Pharmacological Society