Gray Pearson, PhD

Assistant Professor
Simmons Comprehensive Cancer Center, Pharmacology
Graduate Program: Cancer Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-4190
Office Fax: 214-648-7084

gray.pearson@utsouthwestern.edu

Education

Graduate SchoolUniversity of Texas Southwestern Med Ctr Dallas, Cell Biology (2002)
UndergraduateCornell University, Biology (1997)

Research Interests

Breast Cancer
Cell motility and invasion
Epithelial-to Mesenchymal Transition
Metastasis
Tumor microenvironment

Publications

Featured
Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion.

Dang TT, Prechtl AM, Pearson GW, Cancer research, 2011 Oct;

Featured
Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells.

Pearson GW, Hunter T, The Journal of cell biology, 2007 Dec; 179 (7)

PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture.

Pearson GW, Hunter T, Breast cancer research : BCR, 2009 ; 11 (3)

Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signals.

Pearson GW, Earnest S, Cobb MH, Molecular and cellular biology, 2006 Apr; 26 (8):3039-47

Cell condition-dependent regulation of ERK5 by cAMP.

Pearson GW, Cobb MH, The Journal of biological chemistry, 2002 Dec; 277 (50):48094-8

ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation.

Pearson G, English JM, White MA, Cobb MH, The Journal of biological chemistry, 2001 Mar; 276 (11)

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation.

Pearson G, Bumeister R, Henry DO, Cobb MH, White MA, The Journal of biological chemistry, 2000 Dec; 275 (48)