Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models

Liu, Z., Xie, J., Wu, T., Thao, T., Auchus, R. J., and Huang, C.-L. , Hum. Mol. Genet. , 2011; (20):855-866

Identification and functional characterization of Kir2.6 mutations associated with non-familial hypokalemic periodic paralysis

Cheng CJ, Lin SH, Lo YF, Yang SS, Hsu YJ, Cannon SC, Huang CL, , 2011; 286 (31):27425-27435

Regulation of ROMK channel and K+ homeostasis by kidney-specific WNK1 kinase

Liu, Z., Wang, H-R., and Huang, C.-L. , J. Biol. Chem. , 2009; (284):12198-12206

Endothelial expression of WNK1 is essential for angiogenesis and cardiovascular development in mice.

Xie, J., Wu, T., Xu, K., Huang, I. K., Cleaver, D., and Huang, C.-L. , Am. J. Pathology , 2009; (175):1315-1327

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

Cha, S.-K., Ortega, B., Kurosu, H., Rosenblatt K. P., Kuro-o, M, and Huang, C.-L. , Proc. Natl. Acad. Sci USA , 2008; (105):9805-9810

Intersectin links WNK kinases to endocytosis of ROMK

He, G., Wang, H.-R., Huang, S.-K., and Huang, C.-L. , J. Clin. Invest. , 2007; (117):1078-1087

Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms

Lazrak, A., Liu, Z., and Huang, C.-L. , Proc. Natl. Acad. Sci. USA , 2006; (103):1615-1620

Conformational changes of pore helix coupled to gating of TRPV5 by protons

Yeh, B.-I., Kim, Y. K., Jabbar, W., and Huang, C.-L. , EMBO J. , 2005; (24):3224-3234

Regulation of ROMK1 channel by protein kinase A via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism

Liou, H.-H., Zhou, S.S., and Huang C.-L. , Proc. Natl. Acad. Sci. USA , 1999; (96):5820-5825

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by GΒγ.

Huang, C.-L., Feng, S. and Hilgemann, D.W. , Nature , 1998; (391):803-806