Shirley Yan, MD

Assistant Professor
Pathology
Download Curriculum Vitae

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-5022
Office Fax: 214-645-5020

shirley.yan@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Education

FellowshipHahnemann University Hospital, Cytopathology (2008)
ResidencyBaylor Medical Center of Dallas, Pathology (2007)
ResidencyAllegheny General Hospital (2005)
FellowshipUT Southwestern Medical Center, Internal Medicine (2001)
Medical SchoolHeBei Medical School (1982)

Research Interests

CD4+ and CD8+ T-cell responses in the pathogenesis and regulation of multiple sclerosis.
Cytopathology
Endocrine Pathology
Heart and Lung Transplant Pathology

Publications

Featured
Clonal composition of neuroantigen-specific CD8+ and CD4+ T-cells in multiple sclerosis.

Biegler BW, Yan SX, Ortega SB, Tennakoon DK, Racke MK, Karandikar NJ, Journal of neuroimmunology, 2011 May; 234 (1-2):131-40

Featured
Glatiramer acetate (GA) therapy induces a focused, oligoclonal CD8+ T-cell repertoire in multiple sclerosis.

Biegler BW, Yan SX, Ortega SB, Tennakoon DK, Racke MK, Karandikar NJ, Journal of neuroimmunology, 2006 Nov; 180 (1-2):159-71

Featured
Enhanced alveolar growth and remodeling in Guinea pigs raised at high altitude.

Hsia CC, Carbayo JJ, Yan X, Bellotto DJ, Respiratory physiology & neurobiology, 2005 May; 147 (1):105-15

Featured
High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay.

Crawford MP, Yan SX, Ortega SB, Mehta RS, Hewitt RE, Price DA, Stastny P, Douek DC, Koup RA, Racke MK, Karandikar NJ, Blood, 2004 Jun; 103 (11):4222-31

Featured
Retinoic acid-induced alveolar cellular growth does not improve function after right pneumonectomy. PubMed PMID: 14617528.

Merrill D. Dane, Xiao Yan, Rahul M. Tamhane, Robert L. Johnson Jr., Aaron S. Estrera, Deborah C. Hogg, Richard T. Hogg, and Connie C. W. Hsia, Journal of Applied Physiology, 2004; Mar; 9(3) (Epub 2003 Sep 23):1090-1096

Featured
Retinoic acid induces nonuniform alveolar septal growth after right pneumonectomy. PubMed PMID: 14506099.

Xiao Yan, Dennis J. Bellotto, David J. Foster, Robert L. Johnson, Jr., Herbert K. Hagler, Aaron S. Estrera, and Connie C. W. Hsia, Journal of Applied Physiology , 2004; Mar;96(3). (Epub 2003 Nov 14):1080-1089

Featured
Variation of lung volume after fixation when measured by immersion or Cavalieri method. PubMed PMID: 12388332.

Yan, X., E.R. Weibel, and C.C.W. Hsia, American Journal of Physiology, 2003; 2003 Jan;284(1):L242-5. Epub 2002 Sep 13 (Lung Cellular and Molecular Physiology ):242-5

Featured
Expression of epidermal growth factor and surfactant proteins during postnatal and compensatory lung growth. PubMed PMID: 12376351.

Foster DJ, Yan X, Bellotto DJ, Moe OW, Hagler HK, Estrera AS, Hsia CC., American Journal of Physiology, 2002; 283(5) (2002 Nov):L981-90.

Featured
Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis. PubMed PMID: 11877472.

Karandikar NJ, Crawford MP, Yan X, Ratts RB, Brenchley JM, Ambrozak DR, Lovett-Racke AE, Frohman EM, Stastny P, Douek DC, Koup RA, Racke MK., Journal of Clinical Investigation , 2002; 109(5) (Mar):581-4.

Featured
Preliminary observation of the inhibitory effect of (s)-DHPA on the infection of EHFV in sucking mice.

Yan, X., and H. Xiong, Virologica Sinica , 1989; ((1989) 3:262-265):262-265