Michael White, PhD

Professor
Endowed Title: Grant A. Dove Chair for Research in Oncology
Sherry Wigley Crow Cancer Research Endowed Chair, in Honor of Robert Lewis Kirby, M.D.
Cell Biology
Graduate Program: Cancer Biology
Cell Regulation

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-2861
Office Fax: 214-648-8694

michael.white@utsouthwestern.edu

Education

Graduate SchoolUniversity of North Carolina at Chapel Hill (1992)
UndergraduateUniversity of Iowa (1986)

Research Interests

Cancer
Molecular architecture of growth regulatory signal transduction cascades
Oncogenes
Signal transduction
Tumor Suppressors

Publications

RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

Chien Y, Kim S, Bumeister R, Loo YM, Kwon SW, Johnson CL, Balakireva MG, Romeo Y, Kopelovich L, Gale M Jr, Yeaman C, Camonis JH, Zhao Y, White MA , Cell , October 2006; (6):157-170

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.

Bodemann BO, Orvedahl A, Cheng T, Ram RR, Ou YH, Formstecher E, Maiti M, Hazelett CC, Wauson EM, Balakireva M, Camonis JH, Yeaman C, Levine B, White MA. , Cell , January 2011; (144):253-267

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation.

OU YH, Torres M, Ram R, Formstecher E, Roland C, Cheng T, Brekken R, Wurz R, Tasker A, Polverino T, Tan SL, White MA. , Molecular Cell , February 2011; (41/4):458-470

Functional genomics of chemosensitivity exposes deviant cancer cell regulatory systems.

Whitehurst, A. W., Bodemann, B. O., Cardenas, J., Ferguson, D., Girard, L., Payton, M., Minna, J. D., Michnoff, C., Hao, W., Roth, M. G., Xie X.-J., and White, M. A. , Nature , 2007; (446):815-820

Ras regulates assembly of mitogenic signaling complexes through the novel effector protein IMP.

Matheny, S., Chen, C., Kortum, R., Razidlo, G., Lewis, R., and White, M. A. , Nature , 2004; (427):256-260