Iwona Stroynowski, PhD

Professor
Immunology, Microbiology
Graduate Program: Immunology
Molecular Microbiology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-1414
Office Fax: 214-648-1418

iwona.stroynowski@utsouthwestern.edu

Education

Graduate SchoolStanford University (1979)

Research Interests

Cancer Immunology
Host-Pathogen Interactions
Mucosal Immunity

Publications

Featured
Correction of defects responsible for impaired Qa-2 class Ib MHC expression on melanoma cells protects mice from tumor growth.

Chiang, E.Y., Henson, M. and Stroynowski, I. , J.Immunol. , 2003; (170):4515-4523

Featured
A non-polymorphic MHC class Ib molecule binds a large array of diverse self peptides

Joyce, S., Tabaczewski, P., Angeletti, R.H., Nathenson, S.G. and Stroynowski, I. , J.Exp. Med. , 1994; (179):579-588

Featured
Alternative splicing of class Ib MHC transcripts in vivo leads to the expression of soluble Qa-2 molecules in murine blood.

Tabaczewski, P., Shirwan, H., Lewis, K. and Stroynowski, I. , Proc. Natl. Acad. Sci. USA , 1994; (91):1883-1887

Featured
Regulation of gene expression by interferons: control of the H-2 promoter responses.

Korber, B., Mermod, N., Hood, L. and Stroynowski, I. , Science , 1988; (239):1302-1306

Featured
A single gene encodes soluble and membrane-bound forms of the major histocompatibility Qa-2 antigen: anchoring of the product by a phospholipid tail.

Stroynowski, I., Soloski, M., Low, M.G. and Hood, L. , Cell , 1987; (50):759-768

A murine family of gut-expressed class Ib MHC includes alternatively spliced isoforms of the proposed HLA-G homolog.

Guidry P. and Stroynowski, I. , J. Immunol. , 2005; (175):5248-5259

Hepatocytes express abundant surface class I MHC and efficiently utilize TAP, TPN and LMP components of Ag presentation and processing pathway

Chen, M., Tabaczewski, P., Truscott , S., Van Kaer L. and Stroynowski, I. , J. Immunol. , 2005; (175):1047-1055

Protective immunity to disparate tumors is mediated by a nonpolymorphic class I MHC molecule.

Chiang, E. Y. and Stroynowski, I. , J. Immunol. , 2005; (174):5367-5374

A nonclassical class I MHC molecule restricts CTL-mediated rejection of a syngeneic melanoma tumor.

Chiang, E. Y. and Stroynowski, I. , J. Immunol. , 2004; (173):4394-4401

Honors/Awards

Senior Scholar of Ellison Medical Foundation

(2001)

American Cancer Society Postdoctoral Fellow

(1979)

Professional Associations/Affiliations

American Association for the Advancement of the Sciences

American Association of Immunologists

New York Academy of Sciences

Society for Mucosal Immunology