James Richardson, DVM, PhD

Professor
Pathology, Molecular Biology, Plastic Surgery

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-4006
Office Fax: 214-648-1277

james.richardson@utsouthwestern.edu

Education

Graduate SchoolPurdue University Main Campus (1982)

Research Interests

analysis of murine phenotypes
comparative pathology
developmental biology

Publications

Featured
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

Wang,, D-Z., Chang,, P.S., Wang, Z., Sutherland, L., Richardson, J.A., Small, E., Krieg,, P.A., Olson, E.N. , Cell , 2001; (105):851-862

Featured
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.

Li, K, Li Y., Shelton, J.M., Richardson, J.A., Wang, X., Williams, R.S. , Cell , 2000; (101):389-399

Featured
Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.

Piedrahita, J.A., Oetama, B., Bennett, G.D., van Waes, J., Lacey, S.W., Kamen, B.A., Richardson, J.A., Lark, R.H., Finnell, R.H. , Nature Genetics , 1999; (2):228-232

Featured
Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor-2.

Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R.E., Richardson, J.A., Herz, J. , Cell , 1999; (97):689-701

Featured
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation.

Chemelli, R.M., Willie, J.T., Sinton, C.M., Elmquist, J.K., Scammell, T., Lee, C., Richardson, J.A., Williams, S.C., Xiong, Y., Fitch, T.E., Nakazato, M., Hammer, R.E., Saper, C.B., Yanagisawa, M. , Cell , 1999; (98):437-451

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kB activity.

Sosic, D., Richardson, J.A., Yu, K., Ornitz, D.M., Olson, E.N. , Cell , January 2003; (112):169-180

Control of facial muscle development by MyoR and capsulin.

Lu, J., Bassel-Duby, R., Hawkins, A., Chang, P., Valdez, P., Wu, H., Gan, L., Shelton, J., Richardson, J.A., Olson, E.N. , Science , December 2002; (298):2378-2381

Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor.

Naya, R.J., Black, B.L., Wu, H., Bassel-Duby, R., Richardson, J.A., Hill, J.A., Olson, E.N. , Nature Medicine , 2002; (8):1303-1309

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

Shin, C-H., Liu, Z-P., Passier, R., Zhang, C-L., Wang, D-Z., Harris, T.M., Yamagishi, H., Richardson, J.A., Childs, G., Olson, E.N. , Cell , 2002; (110):725-735

Fibulin-5 is an elastin-binding protein essential for elastic fiber development in vivo.

Yanagisawa, H., Davis, E.C., Starcher, B.C., Ouchi, T., Yanagisawa, M., Richardson, J.A., Olson, E.N. , Nature , 2002; (415):168-71

Honors/Awards

Piper Professor

(2008)

Outstanding Teacher

(2006)

Outstanding Teacher

(2003)

Outstanding Teacher

(2001)

Outstanding Teacher

(1998)

Professional Associations/Affiliations

American Association for Advancement of Science

American Veterinary Medical Association

U T Southwestern Academy of Teachers

United States and Canadian Academy of Pathology

University of Texas Academy of Health Science Education