Julian Peterson, PhD

Professor Emeritus
Biochemistry
Graduate Program: Biological Chemistry
Molecular Biophysics

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-3338
Office Fax: 214-648-8856

julian.peterson@utsouthwestern.edu

Education

Graduate SchoolUniversity of Michigan-Ann Arbor, Biochemistry (1967)
Graduate SchoolUniversity of Michigan-Ann Arbor, Biochemistry (1964)

Research Interests

Electron Transport
Enzyme kinetics
Mechanism of enzymatic oxygen activation
Protein-protein interaction
Site-directed mutagenesis and protein engineering

Publications

"A new approach to the study of protein-protein interaction by FTIR: Complex formation between cytochrome P450BM-3 heme domain and FMN reductase domain"

Kariakin, A., Davydov, D. R., Peterson, J. A., and Jung, C. , Biochemistry , 2002; (41):13514-13525

"Probing the interaction of bovine Cytochrome P450scc (CYP11A1) with adrenodoxin: Evaluating site-directed mutations by molecular modeling"

Usanov, S. A., Graham, S. E., Lepesheva, G. I., Azeva, T. N., Strushkevich, N. V., Gilep, A. A., Estabrook, R. W., and Peterson, J. A. , Biochemistry , 2002; (41):8310-8320

"The pivotal role of water in the mechanism of P450BM-3"

Haines, D. C., Tomchick, D. R., Machius, M., and Peterson, J. A. , Biochemistry , 2001; (40):13456-13465

"Practical, enantiospecific synthesis of 14,15-EET and leukotoxin B (vernolic acid)"

Falck, J. R., Reddy, Y. K., Haines, D. C., Reddy, K. M., Krishna, U. M., Graham, S. E., Murry, B., and Peterson, J. A. , Tetrahedron Lett. , 2001; (42):4131-4133

"Nitration and inactivation of cytochrome P450(BM-3) by peroxynitrite-Stopped-flow measurements prove ferryl intermediates"

Daiber, A., Herold, S., Schoneich, C., Namgaladze, D., Peterson, J. A., and Ullrich, V. , Eur. J. Biochem. , 2000; (267):6729-6739

Professional Associations/Affiliations

American Chemical Society, Biological Chemistry Division

American Society for Biochemistry and Molecular Biology

American Society for Pharmacology and Experimental Therapeutics

International Society for the Study of Xenobiotics

The Protein Society