Yan Peng, MD, PhD

Associate Professor
Pathology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-590-2171
Office Fax: 214-590-1411

yan.peng@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Dr. Yan Peng received her M.D. and Ph.D. degrees from Beijing Medical University (BMU), China in 1986 and 1991, respectively. She completed Pediatric Residency/Chief Resident at BMU and practiced there as a Pediatric Nephrologist till 1993.  After a combined six years of basic research on kidney disease at Mayo Clinic, Rochester, MN and UT-Southwestern Medical Center (UTSW), Dallas, TX, she went to University of Pittsburgh Medical Center (UPMC) for her Pathology Residency in 1999. Upon the completion, she took two one-year fellowship trainings in Breast and Gynecologic Pathology at UPMC and Cytopathology at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, respectively. In 2005, she joined the faculty of the Department of Pathology at UTSW, where she has been practicing Surgical Pathology and Cytopathology till now. She is certified in Anatomic Pathology, Clinical Pathology, and Cytopathology by the American Board of Pathology.

Currently she is an UTSW dedicated Breast Pathologist; a Pathology Consultant for the UTSW weekly Multidisciplinary Breast Cancer Conference and Multidisplinary Gynecologic Oncology Tumor Board; an active member of UTSW Breast Care Executive Committee and Breast Disease Oriented Team of Simmons Cancer Center of UTSW; an active member of UTSW University Hospital Cancer Committee. She has been a co-investigator and active participant in several National Cancer Institute (NCI) breast cancer clinical trials. She is Medical Directors of Diagnostic Immunohistochemistry Laboratory and Tumor Biomarker Image and In Situ Hybridization Analysis Laboratory at UTSW Physician Pathologist Leadership Team for Parkland Health & Hospital System. She was elected to be Faculty Senator by UTSW pathology faculty in 2011.

She has authored and co-authored about 60 published scientific articles, book chapters, and case reports, mainly in the fields of Breast and Gynecologic Pathology, Diagnostic Immunohistochemistry, and Cytopathology. Three of the published articles on breast cancer were selected to be CME/SAM articles by the editorial board of American Journal of Clinical Pathology. She has given multiple invited lectures/presentations on triple-negative breast cancer, a newly classified molecular subtype of breast cancer, and its potential prognostic tumor biomarkers nationally and internationally. She is an active Topic Team Member of Education Best Practices Team of American Society for Clinical Pathology (ASCP), and is responsible for reviewing and grading abstracts and course proposals for the ASCP Annual Meetings and for making recommendations and providing inputs to the Annual Meeting’s Steering Committee.

Her specialties include Breast Cancer and Gynecologic Cancer Pathology, Cytopathology, Diagnostic Immunohistochemistry with a special interest in unknown primary cancer work-up, and prognostic tumor biomarker testing by image analysis and FISH.

 

 

Education

FellowshipBeth Israel Deaconess Medical Center (2005)
ResidencyUniversity of Pittsburgh Medical Center (2004)
FellowshipUT Southwestern Medical Center at Dallas (1999)
FellowshipMayo Clinic Rochester (1995)
Medical SchoolBeijing Medical University (1991)
Graduate SchoolBeijing Medical University (1991)
ResidencyBeijing University Hospital (1989)
Medical SchoolBeijing Medical University (1986)

Research Interests

Breast Cancer and Gynecologic Cancer Pathology
Diagnostic and/or prognostic tumor biomarkers

Publications

Featured
Hormone Receptor Status Rather Than HER-2 Status is Significantly Associated with Increased Ki67 and p53 Expression in Triple-Negative Breast Carcinomas. Am. J Clin. Pathol. 2011;135:230-237 (CME/SAM article) * Pathology resident

Han JS*, Cao D, Molberg KH, Sarode VR, Rao R, Sutton LM* and Peng Y. , Am. J Clin. Pathol. , February 2011; (135)

Featured
Atypical Endosalpingiosis in Axillary Sentinel Lymph Node: A potential Source of False Positive Diagnosis of Metastasis. The Breast J. 2011;17(6):672-3.

Sarode VR, Euhus D, Thompson M* and Peng Y, The Breast Journal, 2011; 6 (17):672-673

Featured
Diagnostic utility of RNA-binding protein LIN28 in primitive ovarian germ cell tumors.Histopathology. 2011;59(3):452-9

Xue D, Peng Y, Wang F, Allan RW and Cao D, Histopathology, 2011; 3 (59):452-459

Featured
Multicentric adenomyoepithelioma of the breast with atypia and associated ductal carcinoma in situ.

Han JS, Peng Y, The breast journal, 2010 Sep-Oct; 16 (5):547-9

Featured
Intratumoral Expression Level of Epidermal Growth Factor Receptor and Cytokeratin 5/6 is Significantly Associated with Nodal and Distant Metastases in Patients with Basal-like Triple-negative Breast Carcinoma. Am. J Clin. Pathol. 2010;134:782-787 (CME/SAM article)

Sutton LM*, Han JS*, Molberg KH, Sarode VR, Cao D, Rakheja D, Sailors J and Peng Y., American Journal of Clinical Pathology, 2010; (134):782-787

Featured
Spontaneous Hematoma of the Breast: Thirty Years after Augmentation. Plast. Reconstr. Surg. 2010; 126(1):41e-42e.

Rasko Y, Saint-Cyr M, Peng Y and Rao R, Plast. Reconstr. Surg. , 2010; 1 (126):41e-42e

Featured
SALL4 is a Novel Sensitive and Specific Marker for Ovarian Primitive Germ Cell Tumors and is Particularly Useful in Distinguishing Yolk Sac Tumor from Clear Cell Carcinoma. Am. J. Surg Pathol. 2009; 33(6):894-904..

Cao D, Guo S, Allan RW, Molberg KH and Peng Y, American Journal of Surgical Pathology, 2009; 6 (33):894-904

Featured
AlloDerm vs. DermaMatrix in Immediate Expander-based Breast Reconstruction: A Comparative Analysis. Plast. Reconstr. Surg. 2009; 123(1):1-6.

Becker S, Saint-Cyr M, Wong C, Dauwe P, Nagarkar P and Peng Y, , 2009; 1 (123):1-6

Featured
A Meta-analysis of Comparing Fine Needle Aspiration and Frozen Section for Evaluating Thyroid Nodules. Diagn Cytopathol. 2008; 36:916-920.

Peng Y and Wang HH, Diagnostic Cytopathology, 2008; (36):916-920

Featured
False Positive Sentinel Lymph Nodes in Breast Cancer Patients Caused by Benign Glandular Inclusions. Am. J Clin. Pathol. 2008; 130: 21-27 (CME article)

Peng Y, Ashfaq R, Ewing G, Leitch AM and Molberg KH, American Journal of Clinical Pathology, 2008; (130):21-27

Books

Practical Breast Pathology, a volume in the Pattern Recognition Series. Kevin O. Leslie and Mark R.Wick (eds.). (Mucin Producing Carcinoma of the Breast; Inflammatory Carcinoma of the Breast; Signet Ring Carcinoma of the Breast.)

Yan Peng, Elsevier (Philadelphia, PA) In press, 2011

Honors/Awards

Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)

UT Southwestern Medical Center (2011)

Three articles on breast cancer were selected to be CME/SAM articles by the Editorial Board of the American Journal of Clinical Pathology

(2010)

Distinguished Young Investigator Award in Medicine

Beijing, China (1993)

Distinguished Scientist Award of Canada China Child Health Foundation

(1992)

Best National Medical Article Award

China (1991)

Outstanding Medical Student Award and Scholarship

Beijing Medical University (1986)