Margaret Pearle, MD, PhD

Professor
Endowed Title: Dr. Ralph C. Smith Distinguished Chair in Urologic Education
Urology, Internal Medicine

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-6853
Office Fax: 214-648-8786

margaret.pearle@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Margaret S. Pearle, M.D., Ph.D.: Professor, Department of Urology, and Center for Mineral Metabolism and Clinical Research. B.A./M.S.: University of Chicago. M.D./Ph.D.: University of Chicago. Residency: Northwestern University Medical School. Fellowship in Endourology and Minimally Invasive Surgery: Washington University, St. Louis. Dr. Pearle is currently a Professor with joint appointments in the Department of Urology and the Mineral Metabolism Center, and is holder of the Ralph C. Smith Distinguished Chair in Urologic Education. Her research interests include evaluation of dietary and medical therapies for kidney stones prevention, assessment of outcomes for minimally invasive surgical treatments and development and assessment of resident teaching tools. In her clinical practice, she primarily sees patients needing medical and/or surgical treatment for kidney stones and patients with some cancers or blockage of the upper urinary tract. She has published and spoken extensively in her area of interest.

Education

FellowshipWashington University School of Medicine (1994)
ResidencyNorthwestern U. Medical Ctr.-Chicago (1993)
InternshipNorthwestern U. Medical Ctr.-Chicago (1988)
Medical SchoolUniversity of Chicago (1987)

Research Interests

Medical therapy for stone disease
Minimally invasive surgical therapy for stone disease
Surgical educaton and use of virtual reality simulation
Surgical educaton and use of virtual reality simulation
Urological outcomes research in endourology and stone disease

Publications

Featured
Urologic Diseases in America Project: Urolithiasis

Pearle, M. S., Calhoun, E. A., Curhan, G. C. and The Urologic Diseases in America Project: , J. Urol. , 2005; (173):848-857

Featured
AUA Nephrolithiasis Guideline Panel. Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations

Preminger, G. M., Assimos, D. G., Lingeman, J. E., Nakada, S. Y., Pearle, M. S., Wolf, J. S. Jr. , J. Urol. , 2005; (173):1991-2000

Featured
Prospective, randomized trial comparing shock wave lithotripsy and ureteroscopy for lower pole calyceal calculi 1 cm or less in size.

Pearle, M. S., Lingeman, J. E., Leveillee, R., Kuo, R., Preminger, G. M., Nadler, R. B., Macaluso, J., Monga, M. Kumar, U., Dushinski, J., Albala, D. M., Wolf, J. S. Jr., Assimos, D., Fabrizio, M., Munch, L, C., Nakada, S. Y., Auge, B., Honey, J., Ogan, K., Pattaras, J., McDougall, E. M., Averch, T., D., Turk, T., Pietrow, P. and Watkins. S. , J. Urol. , 2005; (173):2005-2009

Featured
Cost effectiveness of medical management strategies for nephrolithiasis

Lotan Y., Cadeddu, J.A., Roehrborn, C.G., Pak, C.Y.C. and Pearle, M.S. , J Urol , 2004; (172):667-671

Featured
Effect of ascorbic acid consumption on urinary stone risk factors

Traxer, O., Huet, B., Poindexter, J., Pak, C.Y.C. and Pearle, M.S. , J Urol , 2003; (170):397-401

A randomized, controlled, prospective study validating the acquisition of percutaneous renal collecting system access skills using a computer-based hybrid virtual reality surgical simulator ? phase I.

Knudsen, B. E., Matsumoto, E. D., Chew, B. H., Johnson, B., Margulis, V., Cadeddu, J. A.,. Pearle. M. S., Pautler. S. E., and. Denstedt, J. D. , J. Urol. , 2006; (176):2173-2178

Effect of high and low calcium diet on stone-forming risk during liberal oxalate intake

Matsumoto, E., Heller, H. J., Adams-Huet, B., Brinkely, L. J., Pak, C. Y. C. and Pearle M. S. , J. Urol. , 2006; (176):132-136

The contemporary management of renal and ureteric calculi

Galvin, D. J. and Pearle, M. S. , BJU Int. , 2006; (98):1283-1288

International Comparison of Cost-Effectiveness of Medical Management Strategies for Nephrolithiasis

Lotan, Y., Cadeddu, J. A. and Pearle, M. S. , Urol. Research , 2005; (33):223-230

Effect of cranberry juice consumption on urinary stone risk factors.

Gettman, M., Ogan, K., Brinkley, L., Adams-Huett, B., Pak, C. Y. C., and Pearle, M. S. , J. Urol. , 2005; (174):590-594

Honors/Awards

Gold Cytoscope Award

American Urological Association (2003)

First Place, Samuel Ambrose Socioeconomic Essay Contest at the American Urological Association Annual Meeting in Orlando, Florida

Cost effective treatment of ureteropelvic junction obstruction: A decision tree analysis" (2002)

Ralph Smith Distinguished Chair in Urological Education

(2002)

Royal College of Surgeons Travelling Fellowship

The Royal College of Surgeons (1998)

Professional Associations/Affiliations

American Association of Genitourinary Surgeons

American Urological Association

Endourological Society

Fellow, American College of Surgeons

Research in Calculus Kinetics (R.O.C.K.) Society