Karen Pawlowski, PhD

Assistant Professor
Otolaryngology - Head and Neck Surgery
Graduate Program: Biomedical Engineering

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-2432

karen.pawlowski@utsouthwestern.edu

Biography

Dr. Pawlowski obtained her Bachelor of Science degree in Biology from the University of Minnesota, College of Biological Sciences. Afterward, she supervised the electron microscopy lab of Dr. Ardnt J. Duvall III, the Department of Otolaryngology, University of Minnesota, investigating the vascular permeability of the stria vascularis within the inner ear. Her first publications came from this lab and are published under her maiden name, Robinson.

In 1991, Dr. Pawlowski joined the otologic research laboratory of Dr. Charles G. Wright, the Department of Otolaryngology, Head and Neck Surgery, UT Southwestern. During her time in Dr. Wright’s lab., Dr. Pawlowski continued to co-author several publications with Dr. Wright while completing her Masters of Science degree in Applied Cognition and Science and her Doctorate of Philosophy in Auditory Neuroscience at UT Dallas. Dr. Pawlowski worked as a Research Scientist for the department of Behavioral and Brain Sciences, UT Dallas, investigating the cellular mechanisms involved in hearing loss due to Usher’s syndrome type 1F. She also consulted on otologic projects with Alcon Labs, Fort Worth, Texas, after completing her degree.

Dr. Pawlowski rejoined the Department of Otolaryngology, UT Southwestern Medical Center in 2003 as Assistant Professor. Her current position involves working with colleagues, graduate students and medical residents investigating several issues involving the anatomy and physiology of the temporal bone.

Education

Graduate SchoolUniversity of Texas at Dallas (2000)
Graduate SchoolUniversity of Texas at Dallas (1997)
UndergraduateUniversity of Minnesota Central Office (1981)

Research Interests

Cellular mechanisms involved in sensory neural hearing loss
Investigations of biomedical engineering technologies applied to the temporal bone and auditory system
Role of biofilms in chronic recurrent infections of the temporal bone

Publications

Featured
The mouse Ames Waltzer gene encodes a protocadherin required for the normal development of inner ear neuroepithelial cells

Alagramam KN, Murcia CL, Kwon HY, Pawlowski KS, Wright CG, and Woychik RP , Nature Genetics , 2001; (27(1)):99-102

Featured
An animal model for external ear canal inflammation

Wright CG, Pawlowski KS, Roland PS, and Meyerhoff WL , Laryngoscope; (Also presented at the Southern Section of the American Laryngological, Rhinological, and Otological Society Meeting, St. Petersburg Beach, Fla. Jan. 2000.) , 2000; (110(7)):1112-1118

Featured
Histologic demonstration of glycosaminoglycans in inner ear fluids

Pawlowski KS, Wright CG, Meyerhoff WL , Acta Otolaryngologica (Stockholm) , 1998; (118/4):505-510

Featured
Electrocochleographic evaluation of the guinea pig model of endolymphatic hydrops

Badr-El-Dine M, Gerken GM, Wright CG, Robinson KS, Meyerhoff WL , Annals of Otology Rhinology and Laryngology , 1997; (106/11):934-942

A new spontaneous mutation in the mouse protocadherin 15 gene

Zheng QY, Yu H, Washington JL III, Kisly LB, Kikkawa YS, Pawlowski KS, Wright CG, Alagramam KN , Hearing Research , 2006; (1-2/219):110-20

Progression of inner ear pathology in Ames waltzer mice and the role of protocadherin 15 in hair cell development

Pawlowski KS, Kikkawa YS, Wright CG, Alagramam KN , Journal of the Association for Research in Otolaryngology , 2006; (7(1)):in press

Bacterial Biofilm Formation on a Human Cochlear Implant

Pawlowski KS, Wawro D, Roland PS , Otology and Neurotology , 2005; (26):972-975

Characterization of vestibular dysfunction in the mouse model for Usher syndrome 1F

Alagramam KN, Stahl JS, Jones SM, Pawlowski KS, Wright CG , Journal of the Association for Research in Otolaryngology , 2005; (6(2)):106-118

Anatomy and Physiology of the Cochlea

Pawlowski KS , Ototoxicity , 2004;

Professional Associations/Affiliations

Association for Research in Otolaryngology

Society for Neuroscience