Luis Parada, PhD

Professor and Chairman
Endowed Title: Diana K. and Richard C. Strauss Distinguished Chair in Developmental Biology
Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration
Southwestern Ball Distinguished Chair in Nerve Regeneration Research
Developmental Biology
Graduate Program: Cancer Biology
Neuroscience

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-1951
Office Fax: 214-648-1960

luis.parada@utsouthwestern.edu

Education

Graduate SchoolMassachusetts Institute of Technology (1985)
UndergraduateUniversity of Wisconsin-Madison (1979)

Research Interests

Developmental Neurobiology
Mouse Medels of CNS Tumors
Neurofibromatosis
Neurotrophins
Spinal Cord Injury

Publications

Featured
Neurofibromas in NF1:Schwann cell origin and role of tumor environment

Zhu, Y., Ghosh, P., Charnay, P., Burns, D.K., and Parada, L.F , Science , May 2002; (3;296(5569)):920-922

Featured
Mouse tumor model for neurofibromatosis Type 1

Vogel, K.S., Klesse, L.J., Velasco-Miguel, S., Meyers, K., Rushing, E.J. and Parada, L.F , Science , 1999; (286):2176-2179

Featured
Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons.

Vogel, K.S., Brannan, C.I., Jenkins, N.A., Copeland, N.G. and Parada, L.F , Cell , 1995; (82):733-742

Featured
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Soppet, D., Escandon, E., Maragos, J., Middlemas, D.S., Reid, S.W., Blair, J., Burton, L. E., Stanton, B.R., Kaplan, D.R., Hunter, T., Nikolics, K., and Parada, L.F , Cell , 1991; (65):895-903

Featured
The trk proto-oncogene product: A signal transducing receptor for Nerve Growth Factor

Kaplan, D.R., Hempstead, B.L., Martin-Zanca, D., Chao, M.V., and Parada, L.F , Science , 1991; (252):554-558

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

Zhu, Y., Guignard, F., Zhao, D., Burns, D.K., Mason, R.P., and Parada, L.F , Cancer Cell , 2005; (8(2)):119-130

Honors/Awards

National Academy of Sciences

(2011)

2nd Friederich Von Recklinghausen Award

(2009)

Fellow American Association for the Advancement of Science

(2008)

American Academy of Arts and Sciences

(2007)

Institute of Medicine- NAS

(2007)

Professional Associations/Affiliations

American Association for Cancer Research

American Association for the Advancement of Science

Intl. Society for Stem Cell Research

Society for Developmental Biology

Society for Neuroscience