Eric Olson, PhD

Professor & Chairman
Endowed Title: Annie and Willie Nelson Professorship in Stem Cell Research
Pogue Distinguished Chair in Research on Cardiac Birth Defects
Robert A. Welch Distinguished Chair in Science
Molecular Biology
Graduate Program: Genetics and Development
Integrative Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-1187
Office Fax: 214-648-1196

eric.olson@utsouthwestern.edu

Education

Graduate SchoolBowman Gray School of Medicine (1981)

Research Interests

MicroRNAs
Muscle Development
Stem cells
Transcriptional Regulation

Publications

Featured
Control of stress-dependent cardiac growth and gene expression by a microRNA

Van Rooij, E., Sutherland, L.B., Qi, X., Richardson, J. A., Hill, J., and Olson, E. N. , Science , 2007; (316):575-579

Featured
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

Shin, C.H., Liu, Z.P., Passier, R., Zhang, C.L., Wang, D.Z., Harris, T.M., Yamagishi, H., Richardson, J.A., Childs, G., and Olson, E.N. , Cell , 2002; (110):725-735

Featured
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

Wang, D-Z., Chang, P., Wang, Z., Small, E., Krieg, P. A., and Olson, E. N. , Cell , 2001; (105):851-862

Featured
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy.

Molkentin, J.D., Lu, J., Antos, C.L., Markham, B., Richardson, J., Robbins, J., Grant, S., and Olson, E.N. , Cell , 1998; (93):215-228

Featured
Control of mouse cardiac morphogenesis and myogenesis by the myogenic transcription factor MEF2C.

Lin, Q., Schwarz, J., Buchana, C., and Olson, E.N. , Science , 1997; (276):1404-1407

Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3ζ.

Patrick, D.M., Zhang, C.C., Huiyu, Y.T., Qi, X., Schwartz, R.J., Huang, L., and Olson, E.N. , Genes & Development , 2010; (24):1614-1619

MicroRNA regulatory networks in cardiovascular development.

Liu, N. and Olson, E.N. , Developmental Cell , 2010; (18):510-525

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury.

Xin, M., Small, E.M., Sutherland, L.B., Qi, X., McAnally, J., Plato, C.F., Richardson, J.A., Bassel-Duby, R., and Olson, E.N. , Genes & Development , 2009; (23):2166-2178

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.

van Rooij, E., Quiat, D., Johnson, B.A., Sutherland, L.B., Qi, X., Richardson, J.A., Kelm Jr., R.J., and Olson, E.N. , Developmental Cell , 2009; (17):662-673

MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice.

Williams, A.H., Valdez, G., Moresi, V., Qi, X., McAnally, J., Elliott, J.L., Bassel-Duby, R., Sanes, J.R., and Olson, E.N. , Science , 2009; (326):1549-1554

Honors/Awards

Fondation Lefoulon-Delalande Grand Prize for Science

(2009)

Pollin Prize in Pediatric Research

(2005)

Institute of Medicine

(2001)

National Academy of Sciences

(2000)

Pasarow Award in Cardiovascular Medicine

(2000)

Professional Associations/Affiliations

Editorial Board, Developmental Biology

Editorial Board, Developmental Cell

Editorial Board, Molecular and Cellular Biology

Editorial Board, Proceedings of the National Academy of Sciences

Editorial Board, Science