Jerry Niederkorn, Ph.D.
Professor Emeritus
School Medical School
Department Ophthalmology
Graduate Programs Cancer Biology, Immunology
Biography
Education
- Graduate School
- Central Missouri State Univers (1972), Biology
- Graduate School
- University of Arkansas-Fayette (1977), Zoology
Research Interest
- Biology, Immunology and Therapy of Acanthamoeba Keratitis
- Immunobiology of Autoimmune Dry Eye Disease
- Immunobiology of Corneal Allografts
- Immunological Modulation of Ocular Tumor Metastases
- Transplant and Tumor Rejection Processes within the Eye
Publications
Featured Publications
- Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation.
- Neelam S, Mellon J, Wilkerson A, Niederkorn JY Invest. Ophthalmol. Vis. Sci. 2018 Sep 59 11 4738-4747
- Pathobiology and Immunobiology of Acanthamoeba Keratitis: Insights from Animal Models?.
- Neelam S, Niederkorn JY Yale J Biol Med 2017 Jun 90 2 261-268
- Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens.
- Mo J, Neelam S, Mellon J, Brown JR, Niederkorn JY Invest. Ophthalmol. Vis. Sci. 2017 Jan 58 1 137-148
- Growth and Metastasis of Intraocular Tumors in Aged Mice.
- Han Z, Brown JR, Niederkorn JY Invest. Ophthalmol. Vis. Sci. 2016 May 57 6 2366-76
- Natural Killer T Cells Contribute to Neutrophil Recruitment and Ocular Tissue Damage in a Model of Intraocular Tumor Rejection.
- Ligocki AJ, Niederkorn JY Invest. Ophthalmol. Vis. Sci. 2016 Mar 57 3 813-23
- Role of interferon-? and cytotoxic T lymphocytes in intraocular tumor rejection.
- Ligocki AJ, Brown JR, Niederkorn JY J. Leukoc. Biol. 2015 Nov
- Advances on Non-CD4 + Foxp3+ T Regulatory Cells: CD8+, Type 1, and Double Negative T Regulatory Cells in Organ Transplantation.
- Ligocki AJ, Niederkorn JY Transplantation 2015 Jul
- Immunology of Corneal Allografts: Insights from Animal Models.
- Niederkorn JY J Clin Exp Ophthalmol 2015 Jun 6 3
- Severing Corneal Nerves in One Eye Induces Sympathetic Loss of Immune Privilege and Promotes Rejection of Future Corneal Allografts Placed in Either Eye.
- Paunicka KJ, Mellon J, Robertson D, Petroll M, Brown JR, Niederkorn JY Am. J. Transplant. 2015 Apr
- NKT cells act through third party bone marrow-derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases.
- Sadegh L, Chen PW, Brown JR, Han Z, Niederkorn JY Int. J. Cancer 2015 Feb
Honors & Awards
- Endowment
Royal C. Miller Chair in Age-Related Macular Degeneration Research (2011) - Vice Chair, Research
Department of Ophthalmology (2011) - Visiting Professor
Zhongshan Ophthalmic Center, Sun Yat-sen University, (2007) - Endowment
George A. and Nancy P. Shutt Professorship in Medical Science (1995) - PI
3 NIH R01 Research Grants (0) - PI
NIH CORE Grant (0)
Professional Associations/Affiliations
- Editorial Board , American Journal of Transplantation
- Editorial Board, Current Eye Research
- Editorial Board, Investigative Ophthalmology & Visual Sciences
- Immunology Graduate Program