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Carole Mendelson, PhD
Cell Regulation
Integrative Biology
Contact Information
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390
Office Phone: 214-648-3338
Office Fax: 214-648-8856
Biography
Carole Mendelson received a B.S. in Biology from the City College of New York and a Ph.D. in Zoology from Rutgers University, New Brunswick, N.J. She spent five years as a postdoctoral and then Staff Fellow at the National Institutes of Health in Bethesda, Maryland. She joined the faculty of UT Southwestern in 1978. Research in the Mendelson laboratory is focused on reproductive and perinatal biology and includes: (1) genetic and epigenetic mechanisms in the developmental, hormonal and tissue-specific regulation of the gene encoding SP-A, the major protein of pulmonary surfactant; (2) transcriptional regulation of aromatase (CYP19) gene expression in estrogen-producing tissues and in pathologic states, including endometriosis, cancer and preeclampsia; (3) regulatory mechanisms involved in maintenance of uterine quiescence during pregnancy and activation of contractile genes leading to term and pre-term labor. Dr. Mendelson’s research is funded by the National Institutes of Health and March of Dimes Foundation. She held an NIH MERIT Award from 1998 – 2008.
Dr. Mendelson served as a member of the Board of Scientific Counselors for the National Heart, Lung and Blood Institute, NIH, and currently chairs the Reproductive Scientist Development Program Selection Committee and is a member of the Basil O’Connor Starter Scholar Research Award Advisory Committee. She is active within The Endocrine Society (TES), in which she has chaired a number of committees and served as a member of Council and as Vice President for Basic Scientists from 2008 – 2011. She also has been active in several committees that support the career advancement of women in science and medicine. She was president of Women in Endocrinology of TES. Within UT Southwestern, she co-chairs the Women in Science and Medicine Advisory Committee and chairs the Committee on the Advancement of Women.
Education
| Graduate School | Rutgers University New Brunswick, Zoology (1970) |
| Undergraduate | City College of New York, Biology (1964) |
Research Interests
Publications
Benlhabib H, Mendelson CR, Molecular and cellular biology, 2011 May; 31 (10):1949-58
Renthal NE, Chen CC, Williams KC, Gerard RD, Prange-Kiel J, Mendelson CR, Proceedings of the National Academy of Sciences of the United States of America, 2010 Nov; 107 (48):20828-33
Condon JC, Pancharatnam J, Faust JM, Mendelson CR , Proc Natl Acad Sci USA , 2004; (101):4978-4983
Islam K, Mendelson CR , Mol Endocrinol , 2002; (16):1428-1440
Mendelson CR, Chen C, Boggaram V, Zacharias C, Snyder JM , J Biol Chem , 1986; (261):9938-9943
Evans CT, Ledesma DB, Schulz TZ, Simpson ER, Mendelson CR , Proc Natl Acad Sci USA , 1986; (83):6387-6391
Kumar P, Mendelson CR, Molecular endocrinology (Baltimore, Md.), 2011 Jul; :1513-26
Chen CC, Hardy DB, Mendelson CR, The Journal of biological chemistry, 2011 Dec; 286 (50):43091-102
Maitra M, Wang Y, Gerard RD, Mendelson CR, Garcia CK, The Journal of biological chemistry, 2010 Jul; 285 (29):22103-13
Liu D, Benlhabib H, Mendelson CR, Molecular endocrinology (Baltimore, Md.), 2009 Jun; 23 (6):772-83
Related Links
Honors/Awards
Women in Endocrinology (2010)
The Endocrine Society (2008)
Honor Society (2002)
The Endocrine Society (2001)
Regulation of SP-A Expression in Fetal Lung (1998)