Marlyn Mayo, MD

Associate Professor
Internal Medicine

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

marlyn.mayo@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Dr. Mayo obtained her B.A. degree in Psychology from Northwestern University; Evanston, Illinois in 1986. She obtained her M.D. degree from Baylor College of Medicine; Houston, Texas in 1990. After her internship and residency in Internal Medicine at University of California, Irvine, California (1990-1993), she completed a fellowship in Gastroenterology/Hepatology at the University of Texas Southwestern Medical Center at Dallas, Texas (1993-1996). Dr. Mayo specializes in the diagnosis and management of acute and chronic liver diseases, and she enjoys establishing a friendly and supportive relationship with her patients. Dr. Mayo has a keen interest in immune-mediated liver diseases such as primary biliary cirrhosis, autoimmune hepatitis, autoimmune cholangitis, overlap syndromes, and. cryoglobulinemia. She also has a special interest in the management of itching from liver disease. In the laboratory, Dr Mayo's research focuses on the pathogenesis of autoimmune liver diseases. The molecular events involved in bile duct damage in primary biliary cirrhosis and development of cryoglobulins in hepatitis C are current areas of investigation. She studies how the T cell receptor and other co-stimulatory molecules on the surface of B and T lymphocytes participate in the genesis and chronic perpetuation of autoimmune diseases. Dr. Mayo also conducts clinical trials in the University of Texas Southwestern General Clinical Research Center investigating new treatments for primary biliary cirrhosis.

Education

FellowshipUT Southwestern Medical Center at Dallas, Gastroenterology (1996)
ResidencyUniversity of California, Irvine, Internal Medicine (1993)
InternshipUniversity of California, Irvine, Internal Medicine (1991)
Medical SchoolBaylor College of Medicine (1990)

Research Interests

Pathogenesis of autoimmune liver diseases
Pathogenesis of autoimmune liver diseases
Primary biliary cirrhosis
Primary biliary cirrhosis

Publications

Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment

Selmi C, Mayo MJ, Bach M, Ishibashi H, Invernizzi P, Gish RG, Gordon SC, Wright H, Zweiban B, Podda M, Gerswhin ME , Gastroenterology , 2004; (127):485-492

Primary Biliary Cirrhosis

Mayo MJ, Saboorian H, Thiele DL , Atlas of Gastroenterology , 2003; (3rd edition):2374-2387

Extrahepatic manifestations of hepatitis C

Mayo MJ , American Journal of Medical Sciences , 2003; (325):135-148

Long term efficacy of sertraline: as a treatment for cholestatic pruritus

Browning J, Combes B, Mayo MJ , Am J Gastroenterol , 2003; (98):2736-2741

PBC: The future

Mayo MJ , Clin Liv Dis , 2003; (7):957-969

Professional Associations/Affiliations

American Association for the Study of Liver Diseases