Linda Margraf, MD

Professor
Pathology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-456-2993
Office Fax: 214-456-0779

linda.margraf@utsouthwestern.edu

Education

Graduate SchoolUniversity of South Florida (1985)

Research Interests

Clinical applications of immunohistochemistry and in-situ hybridization
Molecular basis of lung development
Pathology of pediatric brain tumors
Pathology of pediatric lung disease

Publications

Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria.

Rogers RE, DeBerardinis RJ, Klesse LJ, Boriack RL, Margraf LR, Rakheja D. , Pediatric and Developmental Patholology , September 2010; (13(5)):408-411

Cloning and tissue specific expression of the mouse Clara cell 10 kD gene; Comparison of endogenous expression to rabbit uteroglobin promoter driven transgene expression

Margraf LR, Finegold MJ, Stanley LA, Majors A, Hawkins HK, DeMayo FJ. , Journal of Respiratory Cell and Molecular Biology , March 1993; (9):231-238

Predictors of tumor progression among children with gangliogliomas..

El Khashab M, Gargan L, Margraf L, Koral K, Nejat F, Swift D, Weprin B, Bowers DC. , Journal of Neurosurgical Pediatrics , June 2009; (Volume 3 (6)):461-466

Effects of the myc oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumor cells

Chen J, Willingham T, Margraf LR, Schreiber-Agus N, DePinho RA, Nisen PD. , Nature Medicine , July 1995; (1):638-643

Proliferative and metabolic markers in incompletely excised pediatric pilocytic astrocytomas-an assessment of three new variables in predicting clinical outcome.

Margraf LR, Gargan,L, Butt Y, Raghunathan N, Bowers, DC, Neuro-Oncology, 2011; 7 (13):767-774

MTORC1 Activation in Childhood Ependymoma and Response to Sirolimus.

Bowers D, Margraf LR, Gargan L, Kucejova B, Brugarolas J. , Journal of Neuro-Oncology, 2011; 3 (103 ):797-801

Mutation in the type 1B bone morphogenetic protein receptor Alk66 impairs germ-cell differentiation and causes germ-cell tumors in zebrafish

Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga LHJ, Margraf L, Rakheja D, Amatruda F. , Proceedings of the National Academy of Science, 2011; 108 (32):13153-13158

Pediatric renal cell carcinomas with Xp11.2 rearrangements are immunoreactive for hMLH1 and hMSH2 proteins.

Rakheja D, Kapur P, Tomlinson GE, Margraf LR. , Pediatr Dev Pathol , 2006; (8 (6)):615-620

Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents.

Bowers DC, Gargan L, Kapur P, Reish JS, Mulne AF, Shapiro KN, Elterman RD, Winick NJ, Margraf LR. , J Clin Oncolo , 2003; (21 (15)):2968-2973

Prognostic Factors in children and adolescents with low-grade oligodendrogliomas.

Bowers DC, Mulne AF, Weprin B, Bruce DA, Shapiro K, Margraf LR. , J Pediatr Neurosurg , 2002; (37 (2)):57-63

Honors/Awards

President-elect, Society for Pediatric Pathology

(2011)

President's Appreciation Award

National Society for Histotechnology (1999)

Outstanding Resident Presentation Award

Society for Pediatric Pathology Annual Meeting (1990)

Annual Pathology Prize for Academic Excellence

University of South Florida, College of Medicine (1985)

Professional Associations/Affiliations

Pulmonary Pathology Society

Society for Pediatric Pathology

United States and Canadian Academy of Pathology