The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Kawaguchi, Y., Cooper, B., Gannon, M., Ray, M., MacDonald, R.J., Wright, C.V.E. , Nature Genetics , 2002; (32):128-134

Tissue-specific expression of the rat elastase I gene in transgenic mice.

Swift, G.H., Hammer, R.E., MacDonald, R.J., and Brinster, R.L. , Cell , 1984; (38):639-646

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Chirgwin, J.M., Przybyla, A.E., MacDonald, R.J., and Rutter, W.J. , Biochemistry , 1979; (24):5294-5299

Cloning of hormone genes from a mixture of cDNA molecules.

Goodman, H.M., and MacDonald, R.J. , Methods in Enzymology , 1979; (68):75-90

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

Masui, T., Swift, G.H., Deering, T., Shen, C., Coats, W.S., Long, Q. Elsasser, H.P., Magnuson, M.A., and MacDonald, R.J. , Gastroenterology , 2010; (139):270-280

Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord and cerebellum

Henke, RM, Savage, TK, Meredith, DM, Glasgow, SM, Hori, K, Dumas, J, MacDonald, RJ, Johnson, JE , Development , 2009; (136):2845-2954

Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood

Masui, T., Hale, M.A., Swift, G.H., and MacDonald, R.J. , Molecular and Cellular Biology , 2008; (28):5458-5468

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

Masui, T., Long, Q., Beres, T.M., Magnuson, M.A., and MacDonald, R.J. , Genes & Development , 2007; (21):2629-2643

PTF1 is an organ-specific and Notch-independent bHLH complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue RBP-L

Beres, T.M., Masui, T., Swift, G.H., Shi, L., Henke, R.M., and MacDonald, R.J. , Molecular and Cellular Biology , 2006; (26):117-130

Experimental control of pancreatic development and maintenance

Holland, A.M., Hale, M.A., Kagami, H., Hammer, R.E., and MacDonald, R.J. , Proc. Nat. Acad. Sci. USA , 2002; (99):12236-12241