Deirdre Brekken, PhD

Adjunct Assistant Professor
Pharmacology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-633-1322
Office Fax: 214-648-4150

deirdre.brekken@utsouthwestern.edu

Education

Graduate SchoolUniversity of Texas Southwestern Med Ctr Dallas, Biomedical Studies (1998)
UndergraduateVanderbilt University, Biomedical Engineering (1993)

Research Interests

Postdoctoral training

Publications

Featured
Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.

Shu H, Chen S, Bi Q, Mumby M, Brekken DL. , Mol Cell Proteomics , March 2004; (3(3)):279-286

Featured
Species specificity in ribosome biogenesis: a nonconserved phosphoprotein is required for formation of the large ribosomal subunit in Trypanosoma brucei.

Jensen BC, Brekken DL, Randall AC, Kifer CT, Parsons M. , Eukaryot Cell , January 2005; (4(1)):30-35

Featured
Phosphoproteomics: new insights into cellular signaling.

Mumby M and Brekken D , Genome Biol. , 2005; (6(9)):230

Featured
Molecular cloning of Trypanosoma brucei CK2 catalytic subunits: The alpha isoform is nucleolar and phosphorylates the nucleolar protein Nopp44/46.

Park, J.H., Brekken, D.L., Randall, A.C., and Parsons, M. , Mol. Biochem. Parasitol. , 2002; (119):97-106

Featured
Characterization of trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione.

Lueher, D.V. and Phillips, M.A. , J. Biol. Chem. , 1996; (271):17495-17490

Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.

Shu H, Chen S, Bi Q, Mumby M, Brekken DL. , Mol Cell Proteomics , March 2004; (3(3)):279-286

Species specificity in ribosome biogenesis: a nonconserved phosphoprotein is required for formation of the large ribosomal subunit in Trypanosoma brucei.

Jensen BC, Brekken DL, Randall AC, Kifer CT, Parsons M. , Eukaryot Cell , January 2005; (4(1)):30-35

Phosphoproteomics: new insights into cellular signaling.

Mumby M and Brekken D , Genome Biol. , 2005; (6(9)):230

Molecular cloning of Trypanosoma brucei CK2 catalytic subunits: The alpha isoform is nucleolar and phosphorylates the nucleolar protein Nopp44/46.

Park, J.H., Brekken, D.L., Randall, A.C., and Parsons, M. , Mol. Biochem. Parasitol. , 2002; (119):97-106

Polyamine and glutathione biosynthetic enzymes from Trypanosoma brucei and Trypanosoma cruzi.

Kinch, L.N., Brekken, D.L. and Phillips, M.A. , Biology of Parasitism , 2000; :95-119

Professional Associations/Affiliations

American Society for Biochemistry and Molecular Biology

National Postdoctoral Association