Zhi-Ping Liu, PhD

Assistant Professor
Internal Medicine, Molecular Biology
Graduate Program: Genetics and Development

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

zhi-ping.liu@utsouthwestern.edu

Biography

Education
University of Science and Technology of China, BS 1982 Computer Science
Shanghai Institute of Biochemistry, MS 1986 Biochemistry
UT Southwestern Medical Center, PhD 1993 Biophysics

Education

Graduate SchoolUniversity of Texas Southwestern Med Ctr Dallas (1993)
Graduate SchoolBiochemistry Institute China (1986)
UndergraduateUniversity of Science & Technology (1982)

Research Interests

epigentic regulation of cardiac hypertrophy and heart failure
Intracellular signaling
Molecular mechanism of cardiovascular diseases
Transcriptional regulation
Vascular biology

Publications

Featured
Phenotypic Modulation of Smooth Muscle Cells through Interaction of Foxo4 and Myocardin

Liu, ZP, Wang, Z, Yanagisawa, H, Olson, EN , Developmental Cell , 2002; (9):161-270

FoxO4 inhibits atherosclerosis through its function in bone marrow derived cells.

Zhu M, Zhang QJ, Wang L, Li H, Liu ZP, Atherosclerosis, 2011 Oct;

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.

Zhang QJ, Chen HZ, Wang L, Liu DP, Hill JA, Liu ZP, The Journal of clinical investigation, 2011 Jun; 121 (6):2447-56

Tumor-suppressive functions of leucine zipper transcription factor-like 1.

Wei Q, Zhou W, Wang W, Gao B, Wang L, Cao J, Liu ZP, Cancer research, 2010 Apr; 70 (7):2942-50

FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation.

Zhou W, Cao Q, Peng Y, Zhang QJ, Castrillon DH, DePinho RA, Liu ZP, Gastroenterology, 2009 Oct; 137 (4):1403-14

Foxo4 regulates TNFa-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription

Li H, Liang J, Castrillon DH, DePinho RA, Olson EN, Liu Z-P , Molecular and Cellular Biology , 2007; (27):2676-2686

Suppression of proliferation and cardiomyocyte hypertrophy by CHAMP, a cardiac-specific RNA helicase

Liu, ZP, Olson, EN. , Proc Natl Acad Sci USA , 2002; (99):2043-2048

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein

Shin*, CH, Liu*, ZP, Passier*, R, Zhang, CL, Wang, DZ, Harris, TM, Yamagishi, H, Richardson, JA, Childs, G, Olson, EN , Cell , 2002; (110):725-735

CHAMP, a novel cardiac-specific helicase regulated by MEF2C

Liu, ZP, Nakagawa, O, Nakagawa, M, Yanagisawa, H, Passier, R, Richardson, JA, Srivastava, D, Olson, EN , Dev Biol. , 2001; (234):497-509

A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo

Liu, ZP, Galindo, RL, Wasserman, SA , Genes Dev. , 1997; (11):3413-3422