Michael Jessen, MD

Professor & Chairman
Endowed Title: Frank M. Ryburn Jr. Distinguished Chair in Cardiothoracic Surgery and Transplantation
Cardio Thoracic Surgery
Graduate Program: Biomedical Engineering

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-7700
Office Fax: 214-645-7701

michael.jessen@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Michael E. Jessen, M.D. was born and raised in Canada. After graduating from the University of Manitoba School of Medicine in Winnipeg, Canada, he began residency training in General Surgery at the University of Manitoba in Winnipeg, completing this program in 1986. He then spent two years in the Surgical Research Laboratory of Dr. Andrew Wechsler at Duke University studying myocardial metabolism and the biochemistry of myocardial protection. He was awarded a research fellowship from the Canadian Heart Foundation during this time. In 1988 he was invited to join the Residency Program in Thoracic Surgery at Duke University Medical Center and trained there under the direction of Dr. David C. Sabiston, Jr., completing his residency in 1990. He then joined the faculty of the University of Texas Southwestern Medical Center at Dallas, where he remains today as Professor and Vice-Chairman of the Department of Cardiovascular and Thoracic Surgery. He is the holder of The Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery. Dr. Jessen directs an active basic research laboratory that has received funding from the National Institutes of Health, the American Heart Association, and the Texas Advanced Technology Program. His research examines myocardial metabolism, the effects of cardiopulmonary bypass and and a novel technique for long-term cardiac preservation for transplantation. This work has yielded a broad array of publications in the literature. In 1994 he received the Lyndon Baines Johnson Research Award of the Texas Affiliate of the American Heart Association. Dr. Jessen is the Director of the Residency Program in Thoracic Surgery at UT Southwestern and teaches in the Biomedical Engineering Program at Southwestern Graduate School. He has an active clinical practice that focuses on cardiac surgery, surgical electrophysiology, aortic surgery, and cardiac transplantation.

Education

ResidencyDuke University Hospital (1990)
FellowshipDuke University Hospital (1988)
ResidencyUniversity of Manitoba (1986)
InternshipUniversity of Manitoba (1982)
Medical SchoolUniversity of Manitoba (1981)

Research Interests

Biocompatibility of materials for cardiopulmonary bypass and effects of the inflammatory response to extracorporeal circulation
Dynamic organ preservation with continuous perfusion
Metabolic mechanisms of myocardial protection and the effects of substrate modifications on organ protective strategies

Publications

Featured
Effects of amino acids on substrate selection, anaplerosis and left ventricular function in the ischemic reperfused rat heart

Jessen ME, Kovarik TE, Jeffrey FM, Sherry AD, Storey CJ, Chao RY, Ring WS, Malloy CR , J Clinical Invest , Spring 1993; (92):831-839

Featured
Impact of recipient age and procedure type on survival following lung transplantation for interstitial pulmonary fibrosis

Meyer DM, Edwards LB, Torres F, Jessen ME, Novik RJ , Ann Thorac Surg , 2005; (79):950-0

Featured
Myocardial oxygen demand and redox state affect fatty acid oxidation in the potassium arrested heart

Peltz M, He TT, Adams GA, Chao RY, Jessen ME , Surgery , 2004; (136):150-159

Featured
Antifibrinolytic Therapy During Cardiopulmonary Bypass Reduces Proinflammatory cytokine levels: A randomized, double-blind placebo-controlled study of e-Aminocaproic acid and aprotinin

Greilich PE, Brouse CF, Whitten CW, Chi L, DiMaio JM, Jessen ME , J Thorac Cardiovasc Surg , 2003; (126):1498-1503

Featured
Extracorporeal Life Support

Meyer DM, Jessen ME , , 2001;

Perfusion preservation vs. static preservation for cardiac transplantation: Effects on myocardial function and metabolism

Rosenbaum DH, Peltz M, DiMaio JM, Meyer DM, Wait MA, Merritt ME, Brown R, Chao RY, Ring WS, Jessen ME , Journal of Heart Lung Transplantation , 2008; (Volume 27):93-99

Benefits of perfusion preservation in canine hearts stored for short intervals.

Rosenbaum, DH, Peltz, M, Merritt, ME, Thatcher, JE, Sasaki, H, Jessen, ME , J Surg Research , 2007; (140):243-249

Hypothermic circulatory arrest for repair of injuries of the thoracic aorta and great vessels

Peltz M, Douglass D, Meyer DM, Wait MA, DiMaio JM, Ring WS, Jessen ME , Interact Cardiovasc Thorac Surg , 2006; (5):560-565

Pyruvate-modified Perfadex improves lung function after long-term hypothermic storage

Peltz M He TT, Adams GA, Chao RY, Jessen ME, Meyer DM , J Heart Lung Transplantation , 2005; (24):896-903

Perfusion preservation maintains myocardial ATP levels and reduces apoptosis in an ex-vivo rat heart transplantation model

Peltz M, He TT, Adams GA, Koshy S, Burgess SC, Chao RY, Meyer DM, Jessen ME , Surgery , 2005; (138):795-805

Honors/Awards

Lyndon Baines Johnson Research Award

American Heart Association, Texas Affiliate (1994)

Harold Micay Surgical Resident Award

University of Manitoba (1985)

Davis and Geck Surgical Resident Award

University of Manitoba (1984)

Maxwell Rady Scholarship

University of Manitoba (1977)

Isbister Scholarship

University of Manitoba (1976)

Professional Associations/Affiliations

American Association for Thoracic Surgery

American Heart Association, Council on Cardiothoracic and Vascular Surgery

Royal College of Physicians and Surgeons of Canada

Society of Thoracic Surgeons

Thoracic Surgery Directors Association