Scott Grundy, MD, PhD

Professor
Endowed Title: Distinguished Chair in Human Nutrition
Center for Human Nutrition, Internal Medicine, Clinical Nutrition

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-2890

scott.grundy@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Dr. Grundy's major research area is in cholesterol and lipoprotein metabolism. He has published over 300 original papers, and numerous solicited articles and chapters. Notable research accomplishments include the development of methods for measuring cholesterol balance and biliary lipid secretion in humans, identifying the metabolic causes of cholesterol gallstones, defining effects of saturated and unsaturated fats, especially monounsaturated fatty acids, on cholesterol and lipoprotein metabolism, uncovering genetic defects underlying hypercholesterolemia and other forms of dyslipidemia, identifying metabolic defects in hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia, and defining mechanisms of action of several lipid-lowering drugs, notably fibrates and HMG CoA reductase inhibitors (statins).

Education

ResidencyNew York Presbyterian Hospital, Internal Medicine (1971)
FellowshipRockefeller University, Lipid Metabolism (1970)
InternshipJefferson Davis Hospital, Rotating (1963)
Medical SchoolBaylor College of Medicine (1960)

Research Interests

Cholesterol Metabolism
Dietary Fats
Drugs Affecting Lipoprotein Metabolism
Human Genetics
Metabolic Syndrome

Publications

Featured
Cholesterol gallstones: a fellow traveler with metabolic syndrome?

Grundy SM , Am J Clin Nutr. , July 2004; (80(1)):1-2

Featured
Relationship between generalized and upper body obesity to insulin resistance in Asian Indian men.

Chandalia, M., Abate, N., Garg, A., Stray-Gundersen, J., Grundy, S.M. , J Clin Endocrinol Metab , July 1999; (84):2329-2335

Featured
Abnormal metabolism of free fatty acids in hypertriglyceridaemic men: apparent insulin resistance of adipose tissue.

Mostaza, J.M., Vega, G.L., Snell, P., Grundy, S.M. , Journal of Internal Medicine , April 1998; (243):265-274

Featured
Relationship of generalized and regional adiposity to insulin sensitivity in man.

Abate, N., Garg, A., Peshock, R.M., Stray-Gunderson, J., and Grundy, S.M. , Journal of Clinical Investigation , 1995; (96(1)):88-98

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Honors/Awards

Council of Nutrition, Physical Activity, and Metabolism

75th Anniversary Lecture (2002)

American Heart Association

Discovery Award (2000)

American Society of Clinical Nutrition

The E.V. McCollum Award (1998)

Baylor College of Medicine

Distinguished Alumnus (1998)

American Heart Association

Distinguished Achievement Award (1997)

Professional Associations/Affiliations

American Association of Physicians

American Institute of Nutrition

American Society for Clinical Investigation

American Society of Clinical Nutrition

National Academies Institute of Medicine