Kathryn O'Donnell-Mendell, PhD

Assistant Professor
Molecular Biology
Graduate Program: Cancer Biology
Genetics and Development

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-5144
Office Fax: 214-648-5190

kathryn.odonnell@utsouthwestern.edu

Education

Graduate SchoolJohns Hopkins University, Genetics (2005)
UndergraduateCornell University, Biology (1998)

Research Interests

Cancer gene discovery
Mouse models of cancer
Transposon-mediated mutagenesis

Publications

Featured
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT, Cell, 2009; 6 (137):1005-17

Featured
c-Myc-regulated microRNAs modulate E2F1 expression

O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT, Nature, 2005; 7043 (435):839-43

Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs

An W, Dai L, Niewiadomska AM, Yetil A, O’Donnell KA, Han JS, Boeke JD , Mobile DNA , February 2011; (2 (1)):2-12

Plug and play modular strategies for synthetic retrotransposons.

An W, Davis ES, Thompson TL, O'Donnell KA, Lee CY, Boeke JD, Methods (San Diego, Calif.), 2009 Nov; 49 (3)

A descent into the nuage: the maelstrom of transposon control.

O'Donnell KA, Burns KH, Boeke JD, Developmental cell, 2008 Aug; 15 (2)

Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae.

Ben-Aroya S, Coombes C, Kwok T, O'Donnell KA, Boeke JD, Hieter P, Molecular cell, 2008 Apr; 30 (2)

Domesticated DNA transposon proteins mediate retrotransposon control.

O'Donnell KA, Boeke JD, Cell research, 2008 Mar; 18 (3)

Mighty Piwis defend the germline against genome intruders.

O'Donnell KA, Boeke JD, Cell, 2007 Apr; 129 (1)

Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis

O'Donnell KA, Yu D, Zeller KI, Kim JW, Racke F, Thomas-Tikhonenko A, Dang CV., Mol Cell Biol, 2006; 6 (26):2373-86

Honors/Awards

CPRIT Scholar in Cancer Research

(2011)

Damon Runyon Foundation Postdoctoral Fellowship Award

(2006)

AACR Scholar-in-Training Award

(2005)

AACR Scholar-in-Training Award

(2003)

Professional Associations/Affiliations

Genetics and Development

Graduate Program (2011)