Dwight German, PhD

Professor
Psychiatry
Graduate Program: Clinical Psychology
Integrative Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-7385
Office Fax: 214-648-7397

dwight.german@utsouthwestern.edu

Education

Graduate SchoolUniversity of Oklahoma Health Sciences Center (1972)
Graduate SchoolUniversity of Oklahoma Norman Campus (1967)
UndergraduateSouthern Methodist University (1966)

Research Interests

Human post-mortem tissue and animal models of both Parkinsons disease and Alzheimers disease are studied to understand the mechanisms responsible for selective vulnerability of specific populations of neurons. The animal models are also used to study potential therapies.
My lab focuses on the cellular and molecular mechanisms responsible for neurodegenerative and psychiatric diseases.
Post-mortem tissues from individuals with affective disorder are used to identify cellular and molecular alterations to provide insight into the etiology of the disorders.

Publications

Featured
Identification of candidate IgG biomarkers for Alzheimer?s disease via combinatorial library screening.

Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T. , Cell , 2011; (144):132-142

Featured
Elevated pesticide levels in the serum are associated with increased risk for Parkinsons disease.

Richardson, J.R., Shalat, S.L., Buckley, B., Winnik, B., OSuilleabhain, P., Diaz-Arrastia, R., Reisch, J., German, D.C. , Arch. Neurol. , 2009; (66 (7)):870-875

Stereotaxic near-infrared probe for localization during functional neurosurgical procedures: further experience.

Giller, C.A., Liu, H., German, D.C., Dewey, R.B. , J. Neurosurgery , 2009; (110):263-273

Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinsons disease.

Sonsalla, P.K., Zeevalk, G., German, D.C. , Parkinsonism & Related Disorders , 2008; (14 Suppl 2):116-118

Serum biomarkers for Alzheimers disease: proteomic discovery.

German DC, Gurnani P, Nandi A, Garner HR, Fisher W, Diaz-Arrastia R, O’Suilleabhain P, Rosenblatt KP. , Biomedicine & Pharmacotherapy , 2007; (61):383-389

Mouse models of Alzheimers disease.

D.C. German , In - A-beta peptide and Alzheimers disease. C. J. Barrow and D. H. Small, eds. Springer Verlag, London. , 2007; (Chapter 16):259-273

Honors/Awards

Grant Review Committee, Michael J. Fox Foundation

(2010)

Nominator for Kyoto Prize

(2010)

Grant Review Committee, Alzheimers Association

(2009)

Editorial Board, Current Molecular Pharmacology

(2008)

Professional Associations/Affiliations

American Association for the Advancement of Science

Society for Neuroscience