Retinal disease in mice lacking hypoxia-inducible transcription factor-2alpha.

Ding K, Scortegagna M, Seaman R, Birch DG, Garcia JA. , Invest Ophthalmol Vis Sci. , March 2005; (46(3)):1010-6

Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.

Dioum EM, Chen R, Alexander MS, Zhang Q, Hogg RT, Gerard RD, Garcia JA. , Science , June 2009; (324(5932)):1289-93

Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities.

Nanduri J, Wang N, Yuan G, Khan SA, Souvannakitti D, Peng YJ, Kumar GK, Garcia JA, Prabhakar NR. , Proc Natl Acad Sci U S A. , January 2009; (106(4)):1199-204

HIF-2{alpha} regulates murine hematopoietic development in an erythropoietin-dependent manner.

Scortegagna M, Ding K, Zhang Q, Oktay Y, Bennett MJ, Bennett M, Shelton JM, Richardson JA, Moe O, Garcia JA. , Blood , December 2004; (105/8):3133-40

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice.

Scortegagna M, Ding K, Oktay Y, Gaur A, Thurmond F, Yan LJ, Marck BT, Matsumoto AM, Shelton JM, Richardson JA, Bennett MJ, Garcia JA. , Nature Genetics , December 2003; (35/4):331-40

Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy.

Bohensky J, Terkhorn SP, Freeman TA, Adams CS, Garcia JA, Shapiro IM, Srinivas V. , Arthritis Rheum , May 2009; (60(5)):1406-15

Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells.

Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, Garry DJ. , Circ Res. , March 2008; (102(9)):1075-81

HIF-2alpha-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery.

Dioum EM, Clarke SL, Ding K, Repa JJ, Garcia JA. , Invest Ophthalmol Vis Sci. , June 2008; (49(6)):2714-20

Transcriptional regulation during development of the ductus arteriosus.

Ivey KN, Sutcliffe D, Richardson J, Clyman RI, Garcia JA, Srivastava D. , Circ Res , August 2008; (103(4)):388-95

Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin.

Oktay Y, Dioum E, Matsuzaki S, Ding K, Yan LJ, Haller RG, Szweda LI, Garcia JA. , Journal of Biological Chemistry , April 2007; (282(16)):11750-6