David Farrar, PhD

Associate Professor
Immunology, Molecular Biology
Graduate Program: Immunology
Integrative Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-7315
Office Fax: 214-648-7331

david.farrar@utsouthwestern.edu

Education

Graduate SchoolUniversity of Texas Southwestern Med Ctr Dallas (1996)
UndergraduateHouston Baptist University (1989)

Research Interests

Cytokine gene regulation
Cytokine signaling
Host/pathogen interactions
T cell development

Publications

IFN-alpha is not sufficient to drive Th1 development due to lack of stable T-bet expression

Hilario J. Ramos, Ann M. Davis, Thaddeus C. George, and J. David Farrar , The Journal of Immunology , September 2007; (179):3792-3803

Reciprocal responsiveness to interleukin-12 and interferon-a specifies human CD8+ effector versus central memory T-cell fates

Hilario J. Ramos, Ann M. Davis, Alexander G. Cole, John D. Schatzle, James Forman, and J. David Farrar , Blood , May 2009; (113):5516-5525

Blockade of virus infection by human CD4+ T cells via a cytokine relay network

A. M. Davis, K. A. Hagan, L. A. Matthews, G. Bajwa, M. A. Gill, M. Gale Jr., J. D. Farrar , Journal of Immunology , May 2008; (180):6923-6932

Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain

Tyler, D. R., M. E. Persky, L. A. Matthews, S. Chan, and J. D. Farrar , Molecular Immunology , January 2007; (44):1874-1882

Cutting Edge: A T-bet-independent role for IFN-a/b in regulating IL-2 secretion in human CD4+ central memory T cells

Ann M. Davis, Hilario J. Ramos, Laurie S. Davis, and J. David Farrar , Journal of Immunology , December 2008; (181):8204-8208

Regulation of effector and memory T-cell functions by type I interferon.

Huber JP, Farrar JD, Immunology, 2011 Apr; 132 (4):466-74

Honors/Awards

Minority Mentor-Trainee Award

American Association of Immunologists (2006)

Junior Faculty Travel Award

American Association of Immunologists (2005)

Special Fellow Award

The Leukemia Society of America (2001)

Professional Associations/Affiliations

American Association of Immunologists