David Johnson, MD

Professor & Chairman
Endowed Title: Donald W. Seldin Distinguished Chair in Internal Medicine
Internal Medicine

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

david.johnson@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Dr. Johnson joined the UT Southwestern Medical Center faculty on July 1, 2010 as the Donald W. Seldin Distinguished Chair in Internal Medicine and Chairman of the Department of Internal Medicine. From July 1983 until June 2010 Dr. Johnson was a member of the faculty at the Vanderbilt University Medical School where he held the Cornelius A. Craig Chair of Medical & Surgical Oncology and served as the Director of the Division of Hematology and Medical Oncology from 1993 until 2010 and Deputy Director of the Vanderbilt-Ingram Cancer Center from 1998 through June 2010. In 2004-2005, Dr. Johnson served as President of the American Society of Clinical Oncology (ASCO) during which time he helped advance ASCO’s quality of care activity known as the Quality Oncology Practice Initiative (QOPI). He was also instrumental in establishing ASCO’s Cancer Survivorship Program. He is a member of the American Board of Internal Medicine (ABIM) Board of Directors and serves as the Chair of the ABIM Subspecialty Board for Medical Oncology. Dr. Johnson also has served on the Food and Drug Administration’s Oncology Drug Advisory Committee, as chairman of the Thoracic Committee of the Eastern Cooperative Oncology Group and on the Board of Directors of the National Comprehensive Cancer Network, the International Association for the Study of Lung Cancer and the LiveSTRONG Foundation. Dr. Johnson’s research interests involve understanding the biology of lung cancer and improving the treatment of this and other solid tumors. He played a key role in the development of the new targeted drugs bevacizumab (Avastin) and erlotinib (Tarceva) both of which are now FDA-approved for the treatment of lung cancer. He has authored over 330 peer reviewed articles, 40 book chapters and edited four oncology textbooks. In 2006 he received the Distinguished Southern Oncologist Award from the Southern Medical Society and the Statesman Award from ASCO in 2008. In 2009 he was elected to the Association of American Physicians. Dr. Johnson earned his medical degree from the Medical College of Georgia and received medical oncology training at Vanderbilt University. He is board certified in internal medicine and medical oncology.

Education

FellowshipVanderbilt University Medical Center, Hematology and Oncology (1983)
ResidencyUniversity of South Alabama Medical Center, Internal Medicine (1979)
InternshipMary Imogene Bassett Hospital, Internal Medicine (1976)
Medical SchoolMedical College of Georgia (1976)

Research Interests

Developmental therapeutics
Eicosanoids in lung cancer

Publications

Featured
Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial

Albain KS, Swann RS, Rusch VW, Turrisi AT, Shepherd FA, Smith C, Chen Y, Livingston RB, Feins RH, Gandara DR, Fry WA, Darling G, Johnson DH, Green MR, Miller RC, Ley J, Sause WT, Cox JD , The Lancet , 2009; (374):379-86

Featured
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH, Dowlati A, Lilenbaum R, Johnson DH , N Engl J Med , 2006; (355):2542-50

Featured
Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer

Winton T, Livingston R, Johnson DH, Rigas J, Johnston M, Butts C, Cormier Y, Goss G, Inculet R, Vallieres E, Fry W, Bethune D, Ayoub J, Ding K, Seymour L, Graham B, Tsao M-S, Gandara D, Kesler K, Demmy T, Shepherd F , N Engl J Med , 2005; (352):2589-97

Featured
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer

Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, Zhu J, Johnson DH , N Engl J Med , 2002; (346):92-8

Featured
A randomized trial of postoperative adjuvant therapy in patients with completely resected stage II or IIIA non-small-cell lung cancer. Eastern Cooperative Oncology Group

Keller SM, Adak S, Wagner H, Herskovic A, Komaki R, Brooks BJ, Perry MC, Livingston RB, Johnson DH , N Engl J Med , 2000; (343):1217-22

Featured
Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide

Turrisi AT, Kim K, Blum R, Sause WT, Livingston RB, Komaki R, Wagner H, Aisner S, Johnson DH , N Engl J Med , 1999; (340):265-71

Clinical course of advanced non-small cell lung cancer patients experiencing hypertension during treatment with bevacizumab in combination with carboplatin and paclitaxel on ECOG 4599.

Dahlberg SE, Sandler AB, Brahmer JR, Schiller JH, Johnson DH , J Clin Oncol , 2010; (28):949-54

Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators.

Wang SE, Yu Y, Criswell TL, Debusk LM, Lin PC, Zent R, Johnson DH, Ren X, Arteaga CL. , Oncogene , 2010; (29):3335-48

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data.

NSCLC Meta-analyses Collaborative Group, Arriagada R, Auperin A, Burdett S, Higgins JP, Johnson DH, Le Chevalier T, Le Pechoux C, Parmar MK, Pignon JP, Souhami RL, Stephens RJ, Stewart LA, Tierney JF, Tribodet H, van Meerbeeck J. , The Lancet , 2010; (375):1267-77

Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib

Miller VA, Riely GJ, Zakowski MF, Li AR, Patel JD, Heelan RT, Kris MG, Sandler AB, Carbone DP, Tsao A, Herbst RS, Heller G, Ladanyi M, Pao W, Johnson DH , J Clin Oncol , 2008; (26):1472-78

Honors/Awards

Chair Elect, American Board of Internal Medicine Board of Directors

(2012)

Association of American Physicians

(2009)

Clinical Research Award, Association of Community Cancer Centers

(2007)

Distinguished Southern Oncologist Award, Southern Association of Oncology

(2006)

President, American Society of Clinical Oncology

(2005)

Professional Associations/Affiliations

American Association for Cancer Research

American College of Physicians

American Society of Clinical Oncology

Association of American Physicians

International Association for the Study of Lung Cancer