Johann Deisenhofer, PhD

Professor
Endowed Title: Virginia and Edward Linthicum Distinguished Chair in Biomolecular Science
Regental Professorship
Biochemistry
Graduate Program: Molecular Biophysics

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-3338
Office Fax: 214-648-8856

johann.deisenhofer@utsouthwestern.edu

Education

Graduate SchoolTechnical University of Munich (1974)

Publications

Featured
Structure of the LDL receptor extracellular domain at endosomal pH.

Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M.S., Goldstein, J.L., and Deisenhofer, J. , Science , 2002; (298):2353-2358

Featured
The crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.

D. Xia, C.-A. Yu, H. Kim, J.-Z. Xia, A.M. Kachurin, L. Zhang, L. Yu & J. Deisenhofer , Science , 1997; (277):60-66

Featured
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats.

B. Kobe & J. Deisenhofer , Nature , 1993; (366):751-756

Featured
The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.

J. Deisenhofer & H. Michel , EMBO J , 1989; (8 (8)):2149-2170

Featured
Crystallographic refinement of the structure of bovine pancreatic trypsin inhibitor at 1.5 A-prime resolution.

Deisenhofer, J., and Steigemann, W. , Acta Crystallographica , 1975; (B31):238-250

Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity.

Y. Huang, R. Baxter, B. Smith, C. Partch, C. Colbert, J. Deisenhofer , Proc. Natl. Acad. Sci. USA , November 2006; (103 (47)):17701-17706

Structure of tracheal cytotoxin in complex with a heterodimeric pattern-recognition receptor.

C.-I. Chang, Y. Chelliah, D. Borek, D. Mengin-Lecreulx & J. Deisenhofer , Science , March 2006; (311 (5768)):1761-1764

Structural basis for conserved complement factor-like function in the antimalarial protein TEP1.

R. H. G. Baxter, C.-I. Chang, Y. Chelliah, S. Blandin, E. A. Levashina, J. Deisenhofer , Proc. Natl. Acad. Sci. USA , July 2007; (104 (28)):11615-11620

Signal transduction pathway of TonB-dependent transporters.

A.D. Ferguson, C.A. Amezcua, N.M. Halabi, Y. Chelliah, M.K. Rosen, R. Ranganathan, J. Deisenhofer , Proc. Natl. Acad. Sci. USA , January 2007; (104 (2)):513-518

NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family.

A.D. Ferguson, V.M. Labunskyy, D.E. Fomenko, Y. Chelliah, D. Arac, C.A. Amezcua, J. Rizo, V.N. Gladyshev & J. Deisenhofer , J. Biol. Chem , February 2006; (281 (6)):3536-3543

Honors/Awards

Nobel Prize in Chemistry

(shared with R. Huber and H. Michel) (1988)

Otto-Bayer-Preis

(shared with H. Michel) (1988)

Biological Physics Prize of the American Physical Society

(shared with H. Michel) (1986)

Professional Associations/Affiliations

Academia Europaea (1989)

American Association for the Advancement of Science (Fellow 1992)

American Crystallographic Association

German Academy of Natural Scientists Leopoldina (2003)

National Academy of Sciences (1997)