Ponciano Cruz, MD

Professor
Endowed Title: Paul R. Bergstresser, M.D., Chair in Dermatology
Dermatology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-2400

ponciano.cruz@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

In addition to serving as Vice Chairman, Dr. Cruz directs the Dermatology Residency Training Program at UT Southwestern. He also serves as Chief of Dermatology at the Dallas VA Medical Center. He directs the Photosensitivity/Phototesting Clinic and the Occupational Skin Disease and Contact Allergy Clinic at UT Southwestern. Dr. Cruz is the recipient of numerous awards and grants for research and teaching, including the American Academy of Dermatology (AAD) Excellence in Eduation Award; NIH research grants; Animal Alternatives Research funding from Procter & Gamble; the Stelwagon Award given by the AAD; and the first Fitzpatrick Research Award given by the Kao Corporation of Japan; gold, silver and bronze awards for teaching posters from the AAD; and the 1989 Outstanding Research Award from the Upjohn Company and the Department of Dermatology at UT Southwestern.

Education

FellowshipUT Southwestern Medical Center at Dallas (1989)
FellowshipUT Southwestern Medical Center at Dallas (1987)
ResidencyUT Southwestern Medical Center at Dallas (1986)
ResidencyKettering Medical Center (1984)
InternshipMakati Medical Center (1980)
Medical SchoolUniversity of the Phillippines (1979)

Publications

Featured
DC-HIL is a negative regulator of T lymphocyte activation.

Chung J-S, Sato K, Dougherty I, Cruz PD Jr., Ariizumi K , Blood , 2007; (109):4320-7

Featured
Syndecan-4 mediates the co-inhibitory function of DC-HIL on T cell activation.

Chung J-S, Dougherty I, Cruz PD Jr, Ariizumi K , J Immunol , 2007; (179):5778-84

Featured
Ultraviolet B radiation upregulates expression of dectin-2 in epidermal Langerhans cells by activating the gene promoter.

Bonkobara M, Yagihara H, Chung J-S, Washizu T, Ariizumi, K, Cruz PD Jr , Photochem Photobiol , 2005; (81):944-8

Featured
Identification and expression of dectin-2 promoter in transgenic mouse.

Gavin ACP, Chung J-S, Sato K, Ariizumi K, Cruz PD Jr. , Exp Dermatol , 2005; (14):281-8

Featured
Freshly isolated spleen dendritic cells and epidermal Langerhans cells undergo similar phenotypic and functional changes during short term culture.

Girolomoni G, Simon JC, Bergstresser PR, Cruz PD Jr. , J Immunol , 1990; (145):2820-6

Acanthosis nigricans

Kia K, Cruz PD Jr. , Treatment of Skin Disease , 2009; (3rd Edition, in press)

Recognition of non-self polysaccharides by C-type lectin receptors dectin-1 and dectin-2.

Hollmig ST, Ariizumi K, Cruz PD Jr. , Glycobiology , 2009; (19/6):568-575

The DC-HIL/syndecan-4 pathway inhibits human allogeneic T cell responses

Chung J-S, Bonkobara M, Tomihari M, Cruz PD Jr., Ariizumi K. , Eur J Immunol , 2009; (in press)

Phototherapy and HIV Infection

McDonald H, Cruz PD Jr. , Dermatological Phototherapy and Photodiagnostic Methods , 2008; (2nd Edition):229-37

Syndecan-4 mediates the co-inhibitory function of DC-HIL on T cell activation.

Chung J-S, Dougherty I, Cruz PD Jr., Ariizumi K. , J Immunol , 2007; (179):5778-84

Honors/Awards

Excellence in Education Award

American Academy of Dermatology (1992)

Fitzpatrick Research Award

Kao Corporation of Japan (1991)

Teacher of the Year

Voted by Derm Residents at UT Southwestern (1991)

Outstanding Research Award

Upjohn Company (1988)

Stelwagon Award

American Academy of Dermatology (1988)

Professional Associations/Affiliations

American Academy of Dermatology

American Board of Dermatology

American Contact Dermatitis Society

American Dermatological Association

Society for Investigative Dermatology