Alexander Gozman, MD

Assistant Professor
Pediatrics

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

alexander.gozman@utsouthwestern.edu

To make an appointment, call 214-730-KIDS (5437).

Education

FellowshipMemorial Sloan-Kettering Cancer Center (2009)
ResidencyChildren's Hospital of Philadelphia (2005)
Medical SchoolBrown University School of Medicine (2002)

Research Interests

Discovery of molecular pathways and new onco-proteins responsible for leukemogenesis
Investigation of Hsp70 inhibitors and their role in the pathogenesis of cancer
Role of Hsp90 inhibitors in pediatric leukemia and their rational translation to clinical practice

Publications

Hsp90 inhibitor PU-H71, a multinodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

Caldas-Lopes E, Cerchietti L, Ahn JH, Clement CC, Robles AI, Rodina A, Moulick K, Taldone T, Gozman A, Guo Y, Wu N, de Stanchina E, White J, Gross SS, Ma Y, Varticovski L, Melnick A, Chiosis G , Proceedings of the National Academy of Sciences of the United States of America , May 2009; (106(20)):8368-73

Targeting Hsp90: small-molecule inhibitors and their clinical development.

Gorelick MH, Atabaki S, Hoyle JD, Dayan PS, Holmes JF, Holubkov R, Monroe D, Callahan J, Kuppermann N, and PECARN TBI Study Group , Current Opinion in Pharmacology , 2008; (8(4)):370-4

Hsal 1 is related to kidney and gonad development and is expressed in Wilms tumor.

Ma Y, Singer DB, Gozman A, Ford D, Chai L, Steinhoff MM, Hansen K, Maizel AL , Pediatric Nephrology , 2001; (16(9)):701-9

Honors/Awards

Weill Cornell Medical College

$75,000 Pilot Award (2009)

Weill Cornell Medical College

$20,000 Planning Award (2008)

Professional Associations/Affiliations

American Society of Hematology