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Rolf Brekken, PhD
Integrative Biology
Contact Information
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390
Office Phone: 214-648-5151
Office Fax: 214-648-4940
Biography
Dr. Rolf Brekken received his Bachelor of Arts degree from Luther College in Decorah, Iowa in 1991 and graduated from UT Southwestern Graduate School of Biomedical Sciences in 1999. His graduate research was focused in the use of Vascular Endothelial Growth Factor (VEGF) as a target for the therapy of solid tumors. In August 2002, he completed his postdoctoral training under Dr. E. Helene Sage in the Department of Vascular Biology at the Hope Heart Institute in Seattle, Washington.
His research interests include angiogenesis and extracellular matrix remodeling in tumors and the development of novel tumor targeting and drug delivery agents for the therapy of pancreatic cancer.
Dr. Brekken is currently the Effie Marie Cain Research Scholar in Angiogenesis Research and is a principal investgator in the Hamon Center for Therapeutic Oncology Research.
Education
| Graduate School | University of Texas Southwestern Med Ctr Dallas (1999) |
| Undergraduate | Luther College (1991) |
Research Interests
Publications
Rivera LB, Brekken RA, The Journal of cell biology, 2011 Jun; 193 (7):1305-19
Schluterman MK, Chapman SL, Korpanty G, Ozumi K, Fukai T, Yanagisawa H, Brekken RA, Disease models & mechanisms, 2010 May-Jun; 3 (5-6):333-42
Arnold SA, Rivera LB, Miller AF, Carbon JG, Dineen SP, Xie Y, Castrillon DH, Sage EH, Puolakkainen P, Bradshaw AD, Brekken RA, Disease models & mechanisms, 2010 Jan-Feb; 3 (1-2):57-72
Dineen SP, Lynn KD, Holloway SE, Miller AF, Sullivan JP, Shames DS, Beck AW, Barnett CC, Fleming JB, Brekken RA. , Cancer Research , June 2008; :PMID: 18519694
Awasthi N, Kirane A, Schwarz MA, Toombs JE, Brekken RA, Schwarz RE, BMC cancer, 2011 ; 11:15
Dineen SP, Roland CL, Greer R, Carbon JG, Toombs JE, Gupta P, Bardeesy N, Sun H, Williams N, Minna JD, Brekken RA, Cancer research, 2010 Apr; 70 (7):2852-61
Arnold SA, Rivera LB, Miller AF, Carbon JG, Dineen SP, Xie Y, Castrillon DH, Sage EH, Puolakkainen P, Bradshaw AD, Brekken RA. , Disease Models and Mechanisms , January 2010; :PMID: 20007485
Sullivan LA, Carbon JG, Roland CL, Toombs JE, Nyquist-Andersen M, Kavlie A, Schlunegger K, Richardson JA, Brekken RA, PloS one, 2010 ; 5 (8):e12031
Roland CL, Lynn KD, Toombs JE, Dineen SP, Udugamasooriya DG, Brekken RA , PLoS One , November 2009; :PMID: 19888452
Arnold SA, Brekken RA. , J Cell Commun Signal , October 2009; :PMID: 19809893
Related Links
Honors/Awards
(2009)
Endowment for Angiogenesis Research - UTSW (2002)
Funded by the American Cancer Society Institutional Research Grant and the Harold C. Simmons Comprehensive Cancer Center (2002)
NIH National Research Service Award, F32 - HL10352 (2000)
Professional Associations/Affiliations
(1992)