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Rolf Brekken, PhD
Integrative Biology
Contact Information
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390
Office Phone: 214-648-5151
Office Fax: 214-648-4940
Biography
Dr. Rolf Brekken received his Bachelor of Arts degree from Luther College in Decorah, Iowa in 1991 and graduated from UT Southwestern Graduate School of Biomedical Sciences in 1999. His graduate research was focused in the use of Vascular Endothelial Growth Factor (VEGF) as a target for the therapy of solid tumors. In August 2002, he completed his postdoctoral training under Dr. E. Helene Sage in the Department of Vascular Biology at the Hope Heart Institute in Seattle, Washington.
His research interests include angiogenesis and extracellular matrix remodeling in tumors and the development of novel tumor targeting and drug delivery agents for the therapy of pancreatic cancer.
Dr. Brekken is currently the Effie Marie Cain Research Scholar in Angiogenesis Research and is a principal investgator in the Hamon Center for Therapeutic Oncology Research.
Education
| Graduate School | University of Texas Southwestern Med Ctr Dallas (1999) |
| Undergraduate | Luther College (1991) |
Research Interests
Publications
Dineen SP, Lynn KD, Holloway SE, Miller AF, Sullivan JP, Shames DS, Beck AW, Barnett CC, Fleming JB, Brekken RA. , Cancer Research , June 2008; :PMID: 18519694
Rivera LB, Brekken RA, The Journal of cell biology, 2011 Jun; 193 (7):1305-19
Schluterman MK, Chapman SL, Korpanty G, Ozumi K, Fukai T, Yanagisawa H, Brekken RA, Disease models & mechanisms, 2010 May-Jun; 3 (5-6):333-42
Arnold SA, Rivera LB, Miller AF, Carbon JG, Dineen SP, Xie Y, Castrillon DH, Sage EH, Puolakkainen P, Bradshaw AD, Brekken RA, Disease models & mechanisms, 2010 Jan-Feb; 3 (1-2):57-72
Arnold SA, Brekken RA. , J Cell Commun Signal , October 2009; :PMID: 19809893
Roland CL, Lynn KD, Toombs JE, Dineen SP, Udugamasooriya DG, Brekken RA , PLoS One , November 2009; :PMID: 19888452
Roland CL, Dineen SP, Lynn KD, Sullivan LA, Dellinger MT, Sadegh L, Sullivan JP, Shames DS, Brekken RA. , Molecular Cancer Therapeutics , July 2009; :PMID: 19567820
Arnold SA, Rivera LB, Miller AF, Carbon JG, Dineen SP, Xie Y, Castrillon DH, Sage EH, Puolakkainen P, Bradshaw AD, Brekken RA. , Disease Models and Mechanisms , January 2010; :PMID: 20007485
Udugamasooriya et al , J. Am. Chem. Soc. , February 2008; (130):5744-5752
Awasthi N, Kirane A, Schwarz MA, Toombs JE, Brekken RA, Schwarz RE, BMC cancer, 2011 ; 11:15
Related Links
Honors/Awards
(2009)
Endowment for Angiogenesis Research - UTSW (2002)
Funded by the American Cancer Society Institutional Research Grant and the Harold C. Simmons Comprehensive Cancer Center (2002)
NIH National Research Service Award, F32 - HL10352 (2000)
Professional Associations/Affiliations
(1992)