Xiaoming Zhan, PhD

Assistant Professor
Physiology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-6000

xiaoming.zhan@utsouthwestern.edu

Biography

PROFESSIONAL EXPERIENCE

 Assistant Professor (Research Track). UT Southwestern, Jun 2009 - Present

 Senior Scientist, Nuvelo Inc. (San Carlos, California), Nov. 2002 - Jan. 2009

 EDUCATION

 Doctor of Philosophy (PhD) in Molecular Biology, December 2002, The University of Texas at Austin,

 Master of Science (MSc) in Genetics, July 1995, Fudan University, Shanghai, China

 Bachelor of Science (BSc) in Genetics and Genetic Engineering, July 1992, Fudan University, Shanghai, China

Education

Graduate SchoolUniversity of Texas at Austin, Molecular Biology (2002)
Graduate SchoolFudan University - China, Genetics (1995)
UndergraduateFudan University - China, Genetics (1992)

Publications

Featured
Genetic analysis of disulfide bond isomerization in E. coli: The Expression of DsbC is modulated by RNase E-dependent mRNA processing

Zhan, X., Gao, J., Jain, C., Cieslewicz, M., Swartz, J. and Georgiou, G. , Journal of Bacteriology , 2004; (186):654-660

Featured
RraA: a Protein Inhibitor of RNase E Activity that Globally Modulates RNA Abundance in E. coli.

Zhan, X. *, Lee, K.*, Gao, J., Qiu, J., Feng, Y., Meganathan, R., Cohen, S.N., and Georgiou, G. * equal contribution , Cell , 2003; (114):623-634

The first propeller domain of LRP6 regulates sensitivity to DKK1.

Binnerts ME, Tomasevic N, Bright JM, Leung J, Ahn VE, Kim KA, Zhan X, Liu S, Yonkovich S, Williams J, Zhou M, Gros D, Dixon M, Korver W, Weis WI, Abo A. , Mol Biol Cell. , August 2009; (15):3552-60

Monoclonal antibodies against IREM-1: potential for targeted therapy of AML.

Korver W, Zhao X, Singh S, Pardoux C, Zhao J, Guzman ML, Sen S, Yonkovich S, Liu S, Zhan X, Tomasevic N, Zhou C, Gros D, Jordan CT, Gotlib J, Hsi ED, Abo A. , Leukemia , April 2009;

Epigenetics in embryonic and adult neurogenesis.

Zhan, X., and Wu, J. , Cell Science Review , 2009; (6):104-128

R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol

Kim KA, Wagle M, Tran K, Zhan X, Dixon MA, Liu S, Gros D, Korver W, Yonkovich S, Tomasevic N, Binnerts M, Abo A. , Biol Cell. , 2008; (19/6):2588-96