Jiang Wu, PhD

Assistant Professor
Endowed Title: Virginia Murchison Linthicum Scholar in Medical Research 2009-2013
Physiology, Developmental Biology
Graduate Program: Genetics and Development
Neuroscience

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-6000

jiang9.wu@utsouthwestern.edu

Education

Graduate SchoolUniversity of Texas at Austin, Molecular Biology (2001)
Graduate SchoolFudan University - China, Genetics (1995)
UndergraduateFudan University - China, Genetics (1992)

Research Interests

activity-dependent gene expression
Chromatin remodeling
neural development
neural stem cell differentiation

Publications

Featured
Dual role of Brg chromatin remodeling factor in Shh signaling during neural development

Zhan, X., Shi, X., Zhang, Z., Chen, Y., and Wu, J.I. , Proc. Natl. Acad. Sci. USA , 2011; (In press)

Featured
Regulation of dendritic development by neuron-specific chromatin remodeling complexes

Wu, J. I., Lessard, J., Olave, I. A., Qiu, Z. Ghosh, A., Graef, I. A., and Crabtree, G. R. , Neuron , 2007; (56):94-108

Featured
An essential switch in subunit composition of a chromatin remodeling complex during neural development

Lessard, J.*, Wu, J. I.*, Ranish, J. A., Wan, M., Winslow, M. M., Staahl, B. T., Wu, H., Aebersold, R., Graef, I. A., and Crabtree, G. R. , Neuron , 2007; (55):201-215

Featured
Mind bomb 1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling

Barsi, J.C.*, Rajendra, R.*, Wu, J.I.*, and Artzt, K. , Mech. Dev. , 2005; (122):1106-1117

Dual role of Brg chromatin remodeling factor in Shh signaling during neural development

Zhan, X., Shi, X., Zhang, Z., Chen, Y., and Wu, J.I. , Proc. Natl. Acad. Sci. USA , 2011; (In press)

An embryonic stem cell chromatin remodeling complex, esBAF is essential for embryonic stem cell self-renewal and pluripotency

Ho, L., Ronan, J, Wu, J.I., Staahl, B., Chen, L., Kuo, A., Lessard, J., Nesvizhskii, A., Ranish, J., Crabtree, G.R. , Proc. Natl. Acad. Sci. USA , 2009; (106):5181-5186

An essential switch in subunit composition of a chromatin remodeling complex during neural development

Lessard, J.*, Wu, J. I.*, Ranish, J. A., Wan, M., Winslow, M. M., Staahl, B. T., Wu, H., Aebersold, R., Graef, I. A., and Crabtree, G. R. , Neuron , 2007; (55):201-215

Regulation of dendritic development by neuron-specific chromatin remodeling complexes

Wu, J. I., Lessard, J., Olave, I. A., Qiu, Z. Ghosh, A., Graef, I. A., and Crabtree, G. R. , Neuron , 2007; (56):94-108

Targeted disruption of Mib2 causes exencephaly with a variable penetrance

Wu, J. I., Rajendra, R., Barsi, J.C., Durfee, L., Benito, E., Gao, G., Kuruvilla, M., Hrdlickova, R., Liss, A. S., Artzt, K. , Genesis , 2007; (45):722-727

Honors/Awards

Basil O’Connor starter scholar

(2010)

Whitehall Foundation award

(2010)

Welch Foundation award

(2009)

Endowed Scholar in Biomedical Research

UT Southwestern Medical Center (2008)